3-甲基-2-氧代丁酸钠合成路线 （共 15 条）
反应条件
15NH4Cl; nicotinamide adenine dinucleotide; recombinant glucose dehydrogenase from Bacillus subtilis; recombinant galactomutarotase from Escherichia coli in sodium hydroxide
T=30°C; pH=8.0 - 8.2;
参考文献
Chiriac, Maria; Lupan, Iulia; Bucurenci; Popescu; Palibroda
Journal of Labelled Compounds and Radiopharmaceuticals, 2008 , vol. 51, # 4 p. 171 - 174
反应条件
thionyl chloride
T=0°C; 0.5 h;
参考文献
Rodrigues-Heerklotz, Katia F.; Drandarov, Konstantin; Heerklotz, Joerg; Hesse, Manfred; Werner, Christa
Helvetica Chimica Acta, 2001 , vol. 84, # 12 p. 3766 - 3772
反应条件
Zn(ClO4)2; (R)-15-aminomethyl-14-hydroxy-5,5-dimethyl-2,8-dithialt;9gt;(2,5)pyridinophane in methanol-d1
96 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tachibana, Yoji; Ando, Makoto; Kuzuhara, Hiroyoshi
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 12 p. 3652 - 3656
反应条件
1: NaOH, (2)H2O / 2 h / Ambient temperature
2: NH4Br, sodium cyanoborohydride / methanol / 96 h / Ambient temperature
View Scheme
参考文献
Baldwin; Wan
Tetrahedron, 1981 , vol. 37, # 8 p. 1589 - 1595
反应条件
NADH-H+; tris(hydroxymethyl)methylamine hydrochloride in water
T=30°C; pH=7.5; Enzyme kinetics;
参考文献
Wada, Yusuke; Iwai, Saho; Tamura, Yusuke; Ando, Tomonori; Shinoda, Takeshi; Arai, Kazuhito; Taguchi, Hayao
Bioscience, Biotechnology and Biochemistry, 2008 , vol. 72, # 4 p. 1087 - 1094
