2-氨基-1-甲氧基丙烷合成路线 （共 25 条）
反应条件
CGS027(B) (S)-transaminase; pyridoxal 5'-phosphate; isopropylamine in acetone T=50°C; transamination; P=100 Torr; pH=7.5; 7 h;
参考文献
Mutti, Francesco G.; Kroutil, Wolfgang
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 18 p. 3409 - 3413
反应条件
glucose dehydrogenase; [3H]-L-Alanine; D-glucose; ω-transaminase ATA-103; pyridoxal 5'-phosphate; β-NADP+; lactate dehydrogenase T=30°C; pH=7; 24 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Lavandera, Ivan; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 17 p. 2761 - 2766
反应条件
1: With transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; 2: With [3H]-L-Alanine; transaminase ATA-113 T=30°C; 24 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
1: With transaminase ATA-113; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; 2: With (R)-alanine; transaminase ATA-117 T=30°C; 24 h; aq. phosphate bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
transaminase ATA-113; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
反应条件
hydrogenchloride 2 h; Heating;
参考文献
Hiroi, Kunio; Sato, Shuko
Chemical & Pharmaceutical Bulletin, 1985 , vol. 33, # 6 p. 2331 - 2338
反应条件
BM-ωTA; ωTA ATA-117 102907WW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate buffer;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
ωTA ATA-117 102907WW; Vibrio fluvialis Vf-ωTA 2100208MW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate buffer;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
transaminase ATA-117; pyridoxal 5'-phosphate; sodium 2-oxopropanoate T=30°C; pH=7.0; 24 h; aq. phosphate bufferResolution of racemateEnzymatic reaction; optical yield given as percent ee;
参考文献
Koszelewski, Dominik; Clay, Dorina; Rozzell, David; Kroutil, Wolfgang
European Journal of Organic Chemistry, 2009 , # 14 p. 2289 - 2292
