(8As)-六氢吡咯并[1,2-a]吡嗪-1,4-二酮合成路线 （共 27 条）
参考文献
Journal of the Chemical Society, Chemical Communications, , # 1 p. 85 - 88
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 27 h; Heating;
参考文献
Nazarova, L. S.; Rozonov, Yu. B.; Likhosherstov, A. M.; Morozova, T. V.; Skoldinov, A. P.; et al.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 12 p. 811 - 815
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 12 p. 1445 - 1448
参考文献
Poroschin et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1958 , p. 1129,1130; engl. Ausg. S. 1097
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Heating;
参考文献
Nazarova, L. S.; Rozonov, Yu. B.; Likhosherstov, A. M.; Morozova, T. V.; Skoldinov, A. P.; et al.
Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 12 p. 811 - 815
Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 12 p. 1445 - 1448
反应条件
1.1: 77 percent / CH2Cl2 / 24 h / Heating 2.1: LDA / tetrahydrofuran / 4 h / -78 °C 2.2: tetrahydrofuran / 16 h / -78 °C 3.1: 100 percent / TsOH*H2O / CH2Cl2 / 20 h / 20 °C View Scheme
参考文献
Hendea, Daniela; Laschat, Sabine; Baro, Angelika; Frey, Wolfgang
Helvetica Chimica Acta, 2006 , vol. 89, # 9 p. 1894 - 1909
参考文献
Poroschin et al.
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1958 , p. 1129,1130; engl. Ausg. S. 1097
反应条件
1.1: 77 percent / CH2Cl2 / 24 h / Heating
2.1: LDA / tetrahydrofuran / 4 h / -78 °C
2.2: tetrahydrofuran / 16 h / -78 °C
3.1: 100 percent / TsOH*H2O / CH2Cl2 / 20 h / 20 °C
View Scheme
参考文献
Hendea, Daniela; Laschat, Sabine; Baro, Angelika; Frey, Wolfgang
Helvetica Chimica Acta, 2006 , vol. 89, # 9 p. 1894 - 1909
