5,6,7-三甲氧基异喹啉合成路线 （共 2 条）
反应条件
N-bromosuccinmide; sulfuric acid in tetrahydrofuran
T=25°C; 2 h;
参考文献
Boger, Dale L.; Takahashi, Kanji
Journal of the American Chemical Society, 1995 , vol. 117, # 50 p. 12452 - 12459
反应条件
1: 76 percent / N-bromosuccinimide / tetrahydrofuran / 3 h / Ambient temperature
2: 1.) butyllithium / 1.) hexane, THF, -78 deg C, 15 min, 2.) hexane, THF, 30 min
3: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -60 deg C, 30 min, 2.) CH2Cl2, from -60 deg C to RT
View Scheme
参考文献
Boger, Dale L.; Brotherton, Christine E.
Journal of Organic Chemistry, 1984 , vol. 49, # 21 p. 4050 - 4055
