4-甲氧基苄基异硫氰酸酯合成路线 （共 20 条）
反应条件
in ethyl acetate T=50°C; 0.166667 h;
参考文献
SYNTA PHARMACEUTICALS CORP.
Patent: WO2007/139968 A2, 2007 ;
Location in patent: Page/Page column 163 ;
反应条件
1: With triethylamine in tetrahydrofuran T=0 - 20°C; 1.75 h; 2: With p-toluenesulfonyl chloride in tetrahydrofuran T=0 - 20°C; 1 h;
参考文献
Akinboye, Emmanuel S.; Rosen, Marc D.; Denmeade, Samuel R.; Kwabi-Addo, Bernard; Bakare, Oladapo
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7450 - 7459
反应条件
calcium carbonate in chloroform; water T=20°C; 16 h;
参考文献
Goodyer, Claire L. M.; Chinje, Edwin C.; Jaffar, Mohammed; Stratford, Ian J.; Threadgill, Michael D.
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 19 p. 4189 - 4206
参考文献
Wong, Rince; Dolman, Sarah J.
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3969 - 3971
反应条件
ammonium thiocyanate in acetonitrile T=20°C; 0.25 h;
参考文献
Mokhtari, Babak; Azadi, Roya; Rahmani-Nezhad, Samira
Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6588 - 6589
反应条件
1: ammonium thiocyanate With PPh3.Br2 in acetonitrile T=20°C; 2: p-(OCH3)C6H4CH2OTHP in acetonitrile T=20°C; Title compound not separated from byproducts;
参考文献
Iranpoor, Nasser; Firouzabadi, Habib; Shaterian, Hamid Reza
Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 9 p. 2093 - 2096
反应条件
1: ammonium thiocyanate With APDPP; bromine in acetonitrile T=20°C; 2 h; 2: 4-MeO-C6H4CH2OTMS in acetonitrile T=20°C; 0.0166667 h;
参考文献
Iranpoor, Nasser; Firouzabadi, Habib; Gholinejad, Mohammad
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 8 p. 2010 - 2019
反应条件
1: ammonium thiocyanate With APDPP; bromine in acetonitrile T=20°C; 2 h; 2: (4-methoxyphenyl)methanol in acetonitrile T=20°C; 0.75 h;
参考文献
Iranpoor, Nasser; Firouzabadi, Habib; Gholinejad, Mohammad
Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 8 p. 2010 - 2019
反应条件
pyridine in chloroform T=71°C; 0.666667 h; Microwave irradiation; Overall yield = 80 percent; chemoselective reaction;
参考文献
Bound, D. James; Bettadaiah; Srinivas
Synthetic Communications, 2013 , vol. 43, # 8 p. 1138 - 1144
反应条件
in hexane T=20°C; Title compound not separated from byproducts;
参考文献
Kitamura, Tsugio; Kobayashi, Shinjiro; Taniguchi, Hiroshi
Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1801 - 1805
