3-甲酰基-5-甲氧基-2-乙氧羰基-1H-吲哚合成路线 （共 8 条）
反应条件
trichlorophosphate in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Pagire, Haushabhau S.; Chun, Hang-Suk; Bae, Myung Ae; Ahn, Jin Hee
Tetrahedron, 2013 , vol. 69, # 14 p. 3039 - 3044
反应条件
trichlorophosphate T=20°C; Vilsmeier formylation;
参考文献
Lee, Jae Hong; So, Ju-Hoon; Jeon, Jong Hyun; Choi, Eun Bok; Lee, Yu-Ri; Chang, Young-Tae; Kim, Cheol-Hee; Bae, Myung Ae; Ahn, Jin Hee
Chemical Communications, 2011 , vol. 47, # 26 p. 7500 - 7502
反应条件
trichlorophosphate in 1,2-dichloro-ethane Vilsmeier-Haack reaction; Heating;
参考文献
Hickman; Sturino; Lachance
Tetrahedron Letters, 2000 , vol. 41, # 43 p. 8217 - 8220
反应条件
1: sulfuric acid / Reflux 2: trichlorophosphate / 20 °C View Scheme
参考文献
Lee, Jae Hong; So, Ju-Hoon; Jeon, Jong Hyun; Choi, Eun Bok; Lee, Yu-Ri; Chang, Young-Tae; Kim, Cheol-Hee; Bae, Myung Ae; Ahn, Jin Hee
Chemical Communications, 2011 , vol. 47, # 26 p. 7500 - 7502
反应条件
1: 75 percent / 90percent hydrazine hydrate / 3 h / Heating 2: 80 percent / phosphorus pentasulfide, pyridine / 4 h / Heating 3: 75 percent / 90percent hydrazine hydrate / 5 h / Heating 4: 90 percent / 5 h / Heating View Scheme
参考文献
Monge; Parrado; Font; Fernandez-Alvarez
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1029 - 1035
反应条件
1: 75 percent / 90percent hydrazine hydrate / 3 h / Heating 2: 80 percent / phosphorus pentasulfide, pyridine / 4 h / Heating 3: 75 percent / 90percent hydrazine hydrate / 5 h / Heating 4: 90 percent / ethanol / Heating View Scheme
参考文献
Monge; Parrado; Font; Fernandez-Alvarez
Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 1029 - 1035
反应条件
triethylsilane; trifluoroacetic acid T=20°C; 5 h;
参考文献
Thanigaimalai, Pillaiyar; Konno, Sho; Yamamoto, Takehito; Koiwai, Yuji; Taguchi, Akihiro; Takayama, Kentaro; Yakushiji, Fumika; Akaji, Kenichi; Chen, Shen-En; Naser-Tavakolian, Aurash; Schoen, Arne; Freire, Ernesto; Hayashi, Yoshio
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 372 - 384
反应条件
1: triethylsilane; trifluoroacetic acid / 5 h / 20 °C 2: lithium hydroxide hydrate / tetrahydrofuran; water / 3 h / 20 °C View Scheme
参考文献
Thanigaimalai, Pillaiyar; Konno, Sho; Yamamoto, Takehito; Koiwai, Yuji; Taguchi, Akihiro; Takayama, Kentaro; Yakushiji, Fumika; Akaji, Kenichi; Chen, Shen-En; Naser-Tavakolian, Aurash; Schoen, Arne; Freire, Ernesto; Hayashi, Yoshio
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 372 - 384
