2-(4-甲氧基苯基)-2H-吲唑合成路线 （共 17 条）
反应条件
sodium t-butanolate; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate in toluene
T=90°C;
参考文献
Athersys, Inc.
Patent: US2007/197526 A1, 2007 ;
Location in patent: Page/Page column 19 ;
US 20070197526 A1
反应条件
titanium tetrachloride; triethylamine; zinc in tetrahydrofuran
T=20°C; pH=8; 0.5 h; Inert atmosphere;
参考文献
Sun, Fang; Feng, Xian; Zhao, Xuan; Huang, Zhi-Bin; Shi, Da-Qing
Tetrahedron, 2012 , vol. 68, # 20 p. 3851 - 3855
反应条件
sodium azide in dimethyl sulfoxide
T=120°C; 8 h;
参考文献
Prasad, Avvari N.; Srinivas, Rapelli; Reddy, Benjaram M.
Catalysis Science and Technology, 2013 , vol. 3, # 3 p. 654 - 658
反应条件
MoO2Cl2(dmf)2; triphenylphosphine in toluene
T=150°C; P=15001.5 Torr; 0.166667 h; Microwave irradiation;
参考文献
Moustafa, Ahmed H.; Malakar, Chandi C.; Aljaar, Nayyef; Merisor, Elena; Conrad, Juergen; Beifuss, Uwe
Synlett, 2013 , vol. 24, # 12 art. no. ST-2013-D0283-L, p. 1573 - 1577
反应条件
Cu(II)(MeCOCHCO2Et)2 in water
T=40°C; P=760.051 Torr; 96 h;
参考文献
Joubert, Nicolas; Basle, Emmanuel; Vaultier, Michel; Pucheault, Mathieu
Tetrahedron Letters, 2010 , vol. 51, # 22 p. 2994 - 2997
反应条件
sodium azide; copper oxide; caesium carbonate in dimethyl sulfoxide
T=120°C;
参考文献
Khatun, Nilufa; Gogoi, Anupal; Basu, Pallabita; Das, Prasenjit; Patel, Bhisma K.
RSC Advances, 2014 , vol. 4, # 8 p. 4080 - 4084
反应条件
1.1: NaHMDS / tetrahydrofuran / 0 - 20 °C
1.2: tetrahydrofuran / 20 °C
2.1: 54 percent / Pd(OAc)2; dppf; t-BuONa / toluene / 15 h / 90 °C
View Scheme
参考文献
Song; Yee
Organic letters, 2000 , vol. 2, # 4 p. 519 - 521
反应条件
1.1: NaHMDS / tetrahydrofuran / 0 - 20 °C
1.2: tetrahydrofuran / 20 °C
2.1: 54 percent / Pd(OAc)2; dppf; t-BuONa / toluene / 15 h / 90 °C
View Scheme
参考文献
Song; Yee
Organic letters, 2000 , vol. 2, # 4 p. 519 - 521
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile
T=60°C; Product distribution; Further Variations:Reaction partnersReagents;
参考文献
Taher; Ladwa; Rajan; Weaver
Tetrahedron Letters, 2000 , vol. 41, # 50 p. 9893 - 9897
反应条件
1: 90 percent / 0.03 h / microwave irradiation
2: 82 percent / triethyl phosphite / 0.07 h / 70 - 150 °C / microwave irradiation
View Scheme
参考文献
Varughese, Deepu John; Manhas, Maghar S.; Bose, Ajay K.
Tetrahedron Letters, 2006 , vol. 47, # 38 p. 6795 - 6797
