4-氯吡咯并嘧啶合成路线

1337531-36-87-甲基-5-[1-[[3-(三氟甲基)苯基]乙酰基]-2,3-二氢-1H-吲哚-5-基]-7H-吡咯并[2,3-d]嘧啶-4-胺

参考文献

Axten, Jeffrey M.; Medina, Jesus R.; Feng, Yanhong; Shu, Arthur; Romeril, Stuart P.; Grant, Seth W.; Li, William Hoi Hong; Heerding, Dirk A.; Minthorn, Elisabeth; Mencken, Thomas; Atkins, Charity; Liu, Qi; Rabindran, Sridhar; Kumar, Rakesh; Hong, Xuan; Goetz, Aaron; Stanley, Thomas; Taylor, J. David; Sigethy, Scott D.; Tomberlin, Ginger H.; Hassell, Annie M.; Kahler, Kirsten M.; Shewchuk, Lisa M.; Gampe, Robert T.
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345-35-7邻氟氯苄+

3680-69-14-氯吡咯并嘧啶

171620-43-2

参考文献

Kelley; Davis; McLean; Glen; Soroko; Cooper
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3884 - 3888

3680-69-14-氯吡咯并嘧啶

171620-43-2

参考文献

Chakka, Nagasree; Bregman, Howie; Du, Bingfan; Nguyen, Hanh Nho; Buchanan, John L.; Feric, Elma; Ligutti, Joseph; Liu, Dong; McDermott, Jeff S.; Zou, Anruo; McDonough, Stefan I.; Dimauro, Erin F.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 2052 - 2062

3680-69-14-氯吡咯并嘧啶

186519-92-64-氯-7H-吡咯并[2,3-d]嘧啶-5-甲酸

参考文献

WO2011/146882 A1, ;
WO 2011/146882 A1

3680-69-14-氯吡咯并嘧啶

16754-80-66-氯-9-(beta-D-呋喃核糖基)-7-脱氮嘌呤

参考文献

Ramasamy; Imamura; Robins; Revankar
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3680-69-14-氯吡咯并嘧啶

24391-41-14-氯-7H-吡咯[2,3-d]嘧啶-5-甲腈

参考文献

CONVERGENCE PHARMACEUTICALS LIMITED; WITTY, David R.; NORTON, David; TIERNEY, Jason Paul; LORTHIOIR, Ghislaine; SIME, Mairi; PHILPOTT, Karen Louise
Patent: WO2012/80735 A1, 2012 ;
WO 2012/080735 A1

3680-69-14-氯吡咯并嘧啶

1500-85-26-氨基-7-氮杂嘌呤

参考文献

Klecka, Martin; Pohl, Radek; Cejka, Jan; Hocek, Michal
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 31 p. 5189 - 5193

3680-69-14-氯吡咯并嘧啶

24386-93-45-碘代杀结核菌素

参考文献

Zhang, Liangren; Zhang, Yunlong; Li, Xianghui; Zhang, Lihe
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 4 p. 907 - 912

3680-69-14-氯吡咯并嘧啶

1618-36-64-氯-5-甲基-7H-吡咯并[2,3-d]嘧啶

参考文献

CONVERGENCE PHARMACEUTICALS LIMITED; WITTY, David R.; NORTON, David; TIERNEY, Jason Paul; LORTHIOIR, Ghislaine; SIME, Mairi; PHILPOTT, Karen Louise
Patent: WO2012/80735 A1, 2012 ;
WO 2012/080735 A1

3680-69-14-氯吡咯并嘧啶+

1066-54-2三甲基乙炔基硅

1147014-68-34-三甲基锡乙炔-7H-吡咯并[2,3-d]嘧啶

参考文献

TARGEGEN INC.
Patent: WO2009/55674 A1, 2009 ;
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WO 2009/055674 A1