2-氨基-3'-硝基苯乙酮盐酸盐合成路线 （共 4 条）
反应条件
1: 95 percent / CHCl3 / 24 h 2: 90 percent / conc. HCl / aq. ethanol / 72 h View Scheme
参考文献
Imperial Chemical Industries PLC
Patent: US4423045 A1, 1983 ;
反应条件
hydrogenchloride in ethanol 72 h;
参考文献
Hill, Richard K.; Nugara, Peter N.; Holt, Elizabeth M.; Holland, Kathleen P.
Journal of Organic Chemistry, 1992 , vol. 57, # 3 p. 1045 - 1047
反应条件
1: 52 percent / Br2 / CHCl3 / 0.33 h / Irradiation 2: 95 percent / CHCl3 / 24 h 3: 90 percent / conc. HCl / aq. ethanol / 72 h View Scheme
参考文献
Blau, Lorena; Menegon, Renato Farina; Trossini, Gustavo H. G.; Molino, Joao Vitor Dutra; Vital, Drielli Gomes; Cicarelli, Regina Maria Barretto; Passerini, Gabriela Duo; Bosquesi, Priscila Longhin; Chin, Chung Man
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 142 - 151
反应条件
1: sulfuric acid; nitric acid / 0.25 h / -5 - 5 °C 2: bromine / acetic acid / 0.5 h / 55 °C 3: chloroform / 24 h / 20 °C 4: hydrogenchloride / ethanol / 72 h / 20 °C View Scheme
参考文献
Blau, Lorena; Menegon, Renato Farina; Trossini, Gustavo H. G.; Molino, Joao Vitor Dutra; Vital, Drielli Gomes; Cicarelli, Regina Maria Barretto; Passerini, Gabriela Duo; Bosquesi, Priscila Longhin; Chin, Chung Man
European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 142 - 151
