吗啉-4-基(吡啶-3-基)乙腈合成路线 （共 4 条）
反应条件
NiO2 in tetrahydrofuran T=20°C; 16 h;
参考文献
Yin, Zhiwei; Zhang, Zhongxing; Zhu, Juliang; Wong, Henry; Kadow, John F.; Meanwell, Nicholas A.; Wang, Tao
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4919 - 4923
反应条件
(i) morpholine, (ii) /BRN= 4652394/, H2O; Multistep reaction;
参考文献
Leete,E. et al.
Journal of Organic Chemistry, 1972 , vol. 37, p. 4465 - 4466
反应条件
potassium hydroxide in methanol; tert-butyl alcohol
Ambient temperature;
参考文献
Leete,E. et al.
Journal of Organic Chemistry, 1972 , vol. 37, p. 4465 - 4466
反应条件
1: 1.) NaH / 1.) DMF, hexane, RT, 1 h, 2.) DMF, hexane, RT, 2 h
2: 80 percent / CuSO4*5H2O / methanol; H2O / 10 h
3: 80 percent / 1,8-diazabicyclo<5.4.0>undec-7-ene / benzene / 36 h / Heating
View Scheme
参考文献
Dhavale; Aidhen; Shafique
Journal of Organic Chemistry, 1989 , vol. 54, # 16 p. 3985 - 3987
