2-苯基咪唑并[1,2-a]吡啶-3-甲醛合成路线 （共 16 条）
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate in chloroform T=0 - 5°C; Vilsmeier-Haack Formylation; 2: 2-phenyl-imidazo[1,2-a]pyridine in chloroform T=20°C; Vilsmeier-Haack Formylation; Reflux;
参考文献
Kamal, Ahmed; Reddy, Vangala Santhosh; Karnewar, Santosh; Chourasiya, Sumit S.; Shaik, Anver Basha; Kumar, G. Bharath; Kishor, Chandan; Reddy, M. Kashi; Narasimha Rao; Nagabhushana, Ananthamurthy; Ramakrishna, Kallaganti V. S.; Addlagatta, Anthony; Kotamraju, Srigiridhar
ChemMedChem, 2013 , vol. 8, # 12 p. 2015 - 2025
反应条件
[copperl(II)(1,1,1,5,5,5-hexafluoroacetylacetonate)2] monohydrate; oxygen in N,N-dimethyl-formamide T=105°C; 6.5 h;
参考文献
Wang, Honggen; Wang, Yong; Liang, Dongdong; Liu, Lanying; Zhang, Jiancun; Zhu, Qiang
Angewandte Chemie - International Edition, 2011 , vol. 50, # 25 p. 5678 - 5681
反应条件
sodium hydroxide; water 5 h;
参考文献
Oehler, Elisabeth; El-Badawi, Mahmoud; Zbiral, Erich
Chemische Berichte, 1985 , vol. 118, # 9 p. 4099 - 4130
反应条件
copper diacetate; palladium diacetate in N,N-dimethyl-formamide T=120°C; 3 h; regioselective reaction;
参考文献
Synthesis, , # 2 p. 271 - 276
反应条件
1: 64 percent / ethanol / 48 h / Heating 2: 95 percent / 0.5 N NaOH, H2O / 5 h View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 50 p. 5599 - 5602
参考文献
Anisimova, V. A.; Avdyunina, N. I.; Pozharskii, A. F.; Simonov, A. N.; Talanova, L. N.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1980 , vol. 16, # 4 p. 409 - 417
Khimiya Geterotsiklicheskikh Soedinenii, 1980 , vol. 16, # 4 p. 528 - 537
反应条件
1: 96 percent / 30percent H2O2, Na2CO3 / methanol; H2O / 4 h / 20 °C 2: 64 percent / ethanol / 96 h / Heating 3: 95 percent / 0.5N NaOH / 2 h / Ambient temperature View Scheme
参考文献
Chemische Berichte, , vol. 118, # 9 p. 4099 - 4130
反应条件
1: sodium hydrogencarbonate / ethanol / 5 h / |Reflux 2: trichlorophosphate / 1.5 h / 0 - 80 °C View Scheme
参考文献
Synlett, , vol. 23, # 18 p. 2609 - 2614,6
反应条件
1: 64 percent / ethanol / 48 h / Heating 2: 95 percent / 0.5 N NaOH, H2O / 5 h View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 50 p. 5599 - 5602
反应条件
1: N-bromosuccinmide; toluene-4-sulfonic acid / acetonitrile / 4 h / |Reflux 2: sodium hydrogencarbonate / ethanol / 5 h / |Reflux 3: trichlorophosphate / 1.5 h / 0 - 80 °C View Scheme
参考文献
Synlett, , vol. 23, # 18 p. 2609 - 2614,6
