2,4-双(三氟甲基)苯胺合成路线 （共 5 条）
反应条件
sulfuric acid; dihydrogen peroxide; iron(II) sulfate in water; dimethyl sulfoxide
参考文献
Kino, Tatsuhito; Nagase, Yu; Ohtsuka, Yuhki; Yamamoto, Kyoko; Uraguchi, Daisuke; Tokuhisa, Kenji; Yamakawa, Tetsu
Journal of Fluorine Chemistry, 2010 , vol. 131, # 1 p. 98 - 105
反应条件
hydrazine hydrate beim Erhitzen mit Wassersdampf;
参考文献
I.G.Farbenind.
Patent: DE672371 , 1935 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 25, p. 119
反应条件
1: 12 h / 25 °C 2: concd. H2SO4, concd. HNO3 / 0 - 20 °C 3: concd. HCl / Heating 4: SnCl2*H2O / ethyl acetate; ethanol / 0.58 h / 70 °C View Scheme
参考文献
Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379
反应条件
1: 12 h / 25 °C 2: concd. H2SO4, concd. HNO3 / 0 - 20 °C 3: concd. HCl / Heating View Scheme
参考文献
Keana; Kher; Sui Xiong Cai; Dinsmore; Glenn; Guastella; Huang; Ilyin; Lu; Mouser; Woodward; Weber
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4367 - 4379
反应条件
phosphorus trichoride in toluene
4.5 h; Heating / reflux;
参考文献
Institute of Medicinal Molecular Design, Inc.
Patent: EP1535609 A1, 2005 ;
Location in patent: Page/Page column 126 ;
