2',4'-二羟基-2-苯基苯乙酮合成路线 （共 57 条）
反应条件
sulfuric acid Acetylation;
参考文献
Parmar, Virinder S.; Pati, Hari N.; Azim, Abul; Kumar, Rajesh; Himanshu; Bisht, Kirpal S.; Prasad, Ashok K.; Errington, William
Bioorganic and Medicinal Chemistry, 1998 , vol. 6, # 1 p. 109 - 118
反应条件
1: 88 percent / PPh3; DIAD / tetrahydrofuran / 0.08 h / 20 °C 2: 87 percent / n-Bu4N*HSO4; aq. NaOH / tetrahydrofuran; H2O / 20 °C View Scheme
参考文献
Kim, Young-Woo; Brueggemeier, Robert W
Tetrahedron Letters, 2002 , vol. 43, # 35 p. 6113 - 6115
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran T=20°C; Mitsunobu reaction; 0.0833333 h;
参考文献
Brueggemeier, Robert W.; Kim, Young-Woo; Hackett, John C.
Patent: US2006/183923 A1, 2006 ;
Location in patent: Page/Page column 6 ;
反应条件
potassium carbonate in acetone T=35 - 40°C; 4 h;
参考文献
Jain, A. C.; Paliwal, Poonam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 985 - 988
反应条件
potassium carbonate; benzene
参考文献
Kanagalakshmi, Kanagasabai; Premanathan, Mariappan; Priyanka, Ragunathan; Hemalatha, Balasubramanian; Vanangamudi, Arumugasamy
European Journal of Medicinal Chemistry, 2010 , vol. 45, # 6 p. 2447 - 2452
反应条件
potassium carbonate in acetone 20 h; Heating;
参考文献
Beger, J.; Binte, H.-J.; Brunne, L.; Neumann, R.
Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 3 p. 269 - 277
反应条件
potassium carbonate; acetone
参考文献
Heilbron et al.
Journal of the Chemical Society, 1936 , p. 295,299, 300
Journal of the Chemical Society, 1934 , p. 1311,1581
参考文献
Heilbron et al.
Journal of the Chemical Society, 1936 , p. 295,299, 300
Journal of the Chemical Society, 1934 , p. 1311,1581
反应条件
1: 81.6 percent / morpholine / propan-2-ol / 7 h / 80 °C 2: 42 percent / K2CO3 / dimethylformamide / 4 h / 80 °C View Scheme
参考文献
Vasil'ev, S.A.; Golubushina, G.M.; Kabachnyi, V.I.; Luk'yanchikov, M.S.; Molchanov, G.I.; et al.
Pharmaceutical Chemistry Journal, 1990 , vol. 24, # 9 p. 641 - 645
Khimiko-Farmatsevticheskii Zhurnal, 1990 , vol. 24, # 9 p. 38 - 41
反应条件
1: With tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate in acetone T=20 - 75°C; Baker-VenKataraman transformation; 12 h; 2: With potassium hydroxide in ethanol 0.333333 h; Heating; Further stages.;
参考文献
Dai, DeMing; Weng, LingLing
Journal of Chemical Research, 2007 , # 10 p. 572 - 573
