(4R)-4-[(3R,5S,8S,9S,10S,13R,14S,17R)-3-羟基-10,13-二甲基-2,3,4,5,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基]戊酸合成路线 （共 3 条）
3664-87-7(4R)-4-[(3R,5S,8S,9S,10S,13R,14S,17R)-3-羟基-10,13-二甲基-2,3,4,5,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基]戊酸
→
反应条件
acetic acid; platinum Hydrogenation;
参考文献
Schubert; Damker
Journal fuer Praktische Chemie (Leipzig), 1957 , vol. <4> 4, p. 260,264
→
3664-87-7(4R)-4-[(3R,5S,8S,9S,10S,13R,14S,17R)-3-羟基-10,13-二甲基-2,3,4,5,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基]戊酸
反应条件
Multi-step reaction with 4 steps 1: Br2 2: NaBH4 3: Zn, CH3COOH4: 3percent KOH / methanol
参考文献
Kimura, Koji; Ogura, Michio Steroids, 1988 , vol. 51, # 3-4 p. 337 - 348
→
3664-87-7(4R)-4-[(3R,5S,8S,9S,10S,13R,14S,17R)-3-羟基-10,13-二甲基-2,3,4,5,8,9,11,12,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基]戊酸
反应条件
Multi-step reaction with 3 steps 1: NaBH4 2: Zn, CH3COOH3: 3percent KOH / methanol
参考文献
Kimura, Koji; Ogura, Michio Steroids, 1988 , vol. 51, # 3-4 p. 337 - 348
