2-羟基甲基-1,4-苯二恶合成路线 （共 30 条）
反应条件
sodium tetrahydroborate; titanium tetrachloride in ethylene glycol dimethyl ether T=0 - 20°C;
参考文献
Archiv der Pharmazie, , vol. 347, # 1 p. 32 - 41
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=20°C; Reduction; 0.5 h;
参考文献
European Journal of Medicinal Chemistry, , vol. 35, # 7-8 p. 663 - 676
反应条件
potassium carbonate in butanone 24 h; Heating;
参考文献
European Journal of Medicinal Chemistry, , vol. 20, # 2 p. 117 - 120
反应条件
potassium hydroxide T=120°C; im Druckrohr;
参考文献
Journal de Pharmacie et de Chimie, , vol. <7> 1, p. 98
Chemische Berichte, , vol. 24, p. 2149
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 0.166667 h; deprotection of TMSEC derivat with various catalyst;
参考文献
Tetrahedron Letters, , vol. 22, p. 969 - 972
反应条件
1: potassium carbonate; acetone 2: lithium alanate; diethyl ether View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5373
反应条件
potassium dicarbonate T=210°C;
参考文献
Scientific Papers of the Institute of Physical and Chemical Research (Japan), vol. 3, p. 281
Chem. Zentralbl., , vol. 97, # I p. 3144
反应条件
sodium tetrahydroborate; ozone
参考文献
Tetrahedron Letters, , vol. 35, # 33 p. 6093 - 6096
反应条件
potassium carbonate in ethanol; water T=25 - 60°C; 1 h; Ea, ΔH(excit.), ΔS(excit.), ΔG(excit.); deuterium labeling study on regioselectivity of attack at epibromohydrin; KineticsThermodynamic dataMechanism;
参考文献
Journal of Physical Organic Chemistry, , vol. 7, # 8 p. 395 - 398
参考文献
Annales de Chimie (Cachan, France), , vol. <7> 18, p. 130
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 126, p. 1427
Bulletin de la Societe Chimique de France, , vol. <3> 19, p. 508
