4-羟基-2,5-二甲基-3(2H)呋喃酮合成路线 （共 42 条）
反应条件
potassium hydroxide; hydrogen; sodium iodide; palladium on activated charcoal in methanol; water T=90°C; P=3102.9 Torr; 24 h;
参考文献
Wong, Chi-Huey; Mazenod, Francois P.; Whitesides, George M.
Journal of Organic Chemistry, 1983 , vol. 48, # 20 p. 3493 - 3497
反应条件
hydrogenchloride; sodium hydroxide in water; dimethyl sulfate
参考文献
Tastemaker
Patent: US5412121 A1, 1995 ;
反应条件
hydrogenchloride; sodium hydroxide in water
参考文献
Tastemaker
Patent: US5412121 A1, 1995 ;
反应条件
piperidine; acetic acid in ethanol T=80°C; 24 h;
参考文献
Wong, Chi-Huey; Mazenod, Francois P.; Whitesides, George M.
Journal of Organic Chemistry, 1983 , vol. 48, # 20 p. 3493 - 3497
反应条件
dihydrogen peroxide; potassium hydrogencarbonate in methanol; water; ethyl acetate
反应条件
sodium methylate in methanol 4 h; Ambient temperature;
参考文献
Phytochemistry (Elsevier), , vol. 28, # 2 p. 631 - 633
反应条件
cell-free extract of E. coli TOP 10 pBAD-fsaB containing 33.5 U of FSA activity in water T=20°C; Aldol Reaction; pH=7.5; 72 h; Enzymatic reactionAqueous Na-phosphate buffer with dithiothreitol; Product distribution / selectivity;
参考文献
WO2008/67997 A1, ;
Page/Page column 13-16 ;
反应条件
piperidine; acetic acid in ethanol T=80°C; 2 h;
参考文献
Roscher, Rene; Schreier, Peter; Schwab, Wilfried
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 6 p. 493 - 499
反应条件
oxalic acid in water 3.2 h; Heating;
参考文献
Torii, Sigeru; Inokuchi, Tsutomu; Hirata, Youzou
Synthesis, 1987 , # 4 p. 377 - 379
