(S)-3-羟基-3-苯基丙酸合成路线 （共 64 条）
反应条件
potassium hydroxide in methanol Ambient temperature; Yield given;
参考文献
Angewandte Chemie, , vol. 97, # 10 p. 874 - 876
反应条件
sodium hydroxide; Pseudomonas candida lipase in phosphate buffer T=20°C; resolution of racemate; pH=7.0; 24 h; ultrasound; Product distribution; Further Variations:pH-valuesReagentsmagnetic stirring;
参考文献
Ribeiro, Carlos Magno R.; Passaroto, Elisa N.; Brenelli, Eugenia C.S.
Tetrahedron Letters, 2001 , vol. 42, # 37 p. 6477 - 6479
反应条件
hydrogenchloride in diethyl ether 1 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 51, # 4 p. 471 - 473
反应条件
1: C64H46F8Fe4O2Rh2; triethylamine / methanol; dichloromethane / 3 h / 30 °C / Inert atmosphere 2: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 3.5 h / 20 °C 3: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 3 h / 20 °C View Scheme
参考文献
Chemical Communications, , vol. 47, # 37 p. 10488 - 10490
反应条件
1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane; water / 3.5 h / 20 °C 2: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 3 h / 20 °C View Scheme
参考文献
Chemical Communications, , vol. 47, # 37 p. 10488 - 10490
参考文献
Journal of the American Chemical Society, , vol. 104, # 17 p. 4610 - 4617
反应条件
potassium hydroxide; aluminum amalgam; water 1) THF, 15 to 20 deg C; 2) ethanol, water, 6 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 36, # 2 p. 227 - 236
反应条件
(-)-di-2-isocaranylchloroborane; lithium diisopropyl amide 1.) THF, hexane, 2.) THF; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 60, # 21 p. 7006 - 7009
反应条件
pyridine; ruthenium trichloride; sodium periodate; hydroxide; hydrogen cation; 4-nitro-benzoyl chloride
参考文献
Tetrahedron Letters, , vol. 37, # 44 p. 7893 - 7896
反应条件
pyridine anschliessend Behandeln mit wss. Natronlauge;
参考文献
Chemische Berichte, , vol. 71, p. 9,15
