1,4,5-三苯基-1H-吡唑合成路线 （共 21 条）
反应条件
sodium carbonate; acetic acid in methanol; water T=135°C; Cyclization; pH=4;
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther
Journal of Organic Chemistry, 2000 , vol. 65, # 21 p. 7010 - 7019
反应条件
n-butyllithium; boric acid trimethyl ester in tetrahydrofuran T=-78°C; Dehalogenation; 2 h;
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther
Journal of Organic Chemistry, 2000 , vol. 65, # 21 p. 7010 - 7019
反应条件
1: With n-butyllithium in tetrahydrofuran T=-80°C; Metallation; 2: With trimethylstannyl chloride in tetrahydrofuran T=-80 - 20°C; Dehalogenation;
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther
Synlett, 2000 , # 7 p. 1028 - 1030
反应条件
1: With n-butyllithium in tetrahydrofuran T=-80°C; Metallation; 2: With trimethylstannyl chloride in tetrahydrofuran T=-80 - 20°C; Dehalogenation;
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther
Synlett, 2000 , # 7 p. 1028 - 1030
反应条件
in N,N-dimethyl-formamide 3 h; Reflux;
参考文献
Prakash, Om; Sharma, Deepak; Kamal, Raj; Kumar, Rajesh; Nair, Reshmi R.
Tetrahedron, 2009 , vol. 65, # 49 p. 10175 - 10181
反应条件
1: 75 percent / ethanol / Heating 2: 95 percent / Raney Nickel / ethanol / Heating View Scheme
参考文献
Wislicenus; Ruthing
Justus Liebigs Annalen der Chemie, 1911 , vol. 379, p. 258
反应条件
pyridine T=150°C; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Majumder, Supriyo; Gipson, Kevin R.; Staples, Richard J.; Odom, Aaron L.
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 11-12 p. 2013 - 2023
反应条件
1.1: 90 percent / aq. Na2CO3 / acetic acid; methanol 2.1: BuLi / tetrahydrofuran / -80 °C 2.2: Me3SnCl / tetrahydrofuran / -80 - 20 °C View Scheme
参考文献
Olivera, Roberto; SanMartin, Raul; Dominguez, Esther
Synlett, 2000 , # 7 p. 1028 - 1030
反应条件
1: N-bromosuccinmide / tetrachloromethane / 1 h / 20 °C 2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 90 - 120 °C 3: Raney nickel W4 / ethanol / Reflux View Scheme
参考文献
Khan, Taukeer A.; Kumar, Sarvesh; Venkatesh, Chelvam; Ila, Hiriyakkanavar
Tetrahedron, 2011 , vol. 67, # 16 p. 2961 - 2968
反应条件
1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 90 - 120 °C 2: Raney nickel W4 / ethanol / Reflux View Scheme
参考文献
Khan, Taukeer A.; Kumar, Sarvesh; Venkatesh, Chelvam; Ila, Hiriyakkanavar
Tetrahedron, 2011 , vol. 67, # 16 p. 2961 - 2968
