2-氨基-4-氯-6-苯基嘧啶合成路线 (共 4 条)
反应条件
potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in acetonitrile T=90°C; 4 h;
参考文献
SCHERING CORPORATION
Patent: WO2009/111449 A1, 2009 ;
Location in patent: Page/Page column 38-39 ;
WO 2009/111449 A1
反应条件
trichlorophosphate 1 h; Heating / reflux;
参考文献
BAYER PHARMACEUTICALS CORPORATION
Patent: WO2006/99231 A1, 2006 ;
Location in patent: Page/Page column 37 ;
反应条件
bromine in acetic acid
参考文献
The Upjohn Company
Patent: US4795812 A1, 1989 ;
参考文献
Burroughs Welcome and Co.
Patent: US2691655 , 1952 ;