1: 1-(3-hydroxypropyl)piperidine With sodium hydride in isobutyramide T=50°C; 1 h; 2: methanesulfonic acid 3-(4-chlorophenyl)-propyl ester in isobutyramide T=22 - 25°C; 9 h;

15-crown-5 in toluene 4 h; Heating / reflux;