1: ethanol; aqueous HCl 2: KMnO4; NaOH; aqueous acetone View Scheme

hydrogenchloride; ethanol

Stage #1: <a href="#" onclick="return RXDsubstances(event, this, '385838', constants.ctx, '0')">ethyl acetoacetate</a> <b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4122952', constants.ctx, '0')">sodium hydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102551', constants.ctx, '0')">1,4-dioxane</a> <br />T=0 - 25&deg;C;&nbsp;0.583333&nbsp;h;&nbsp;<br />Stage #2: <a href="#" onclick="return RXDsubstances(event, this, '108582', constants.ctx, '0')">(R)-phenylethylene oxide</a> &nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102551', constants.ctx, '0')">1,4-dioxane</a> <br />T=0&deg;C;&nbsp;14&nbsp;h;&nbsp;&nbsp;Heating / reflux;&nbsp;<br /> <br /> &nbsp;