2',3'-O-异亚丙基胞苷合成路线 (共 9 条)
反应条件
sulfuric acid T=0 - 20°C; 12 h;
参考文献
Purohit, Meena K.; Poduch, Ewa; Wei, Lianhu William; Crandall, Ian Edward; To, Terrence; Kain, Kevin C.; Pai, Emil F.; Kotra, Lakshmi P.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 22 p. 9988 - 9997
反应条件
in acetone 6 h; Inert atmosphere;
参考文献
Shen, Xiao-Min; Zheng, Bi-Yuan; Huang, Xiu-Rong; Wang, Lei; Huang, Jian-Dong
Dalton Transactions, 2013 , vol. 42, # 29 p. 10398 - 10403
反应条件
1: 44 percent / diethyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / Ambient temperature 2: 23 percent / 5 h / Heating View Scheme
参考文献
Kimura, Junji; Yagi, Kentaro; Suzuki, Hideyuki; Mitsunobu, Oyo
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 12 p. 3670 - 3677
反应条件
sodium hydroxide in 1,4-dioxane T=20°C; 45 h; rate of hydrolysis;
参考文献
Bridson, Peter K.; Jiricny, Josef; Kemal, Oeznur; Reese, Colin B.
Journal of the Chemical Society, Chemical Communications, 1980 , # 5 p. 208 - 209
参考文献
Kimura, Junji; Yagi, Kentaro; Suzuki, Hideyuki; Mitsunobu, Oyo
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 12 p. 3670 - 3677
反应条件
sodium hydroxide T=90.1°C; various reagent concentration, decomposition to nonchromophoric products; Rate constantMechanism;
参考文献
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, , vol. 40, # 10 p. 798 - 805
反应条件
erbium(III) triflate in water T=120°C; 0.5 h; Microwave irradiation;
参考文献
Procopio, Antonio; Gaspari, Marco; Nardi, Monica; Oliverio, Manuela; Romeo, Roberto
Tetrahedron Letters, 2008 , vol. 49, # 12 p. 1961 - 1964
反应条件
phosphoric acid; water; phosphorus pentoxide und anschliessend mit H2O;
参考文献
Hayakawa, Y.; Wakabayashi, S.; Nobori, T.; Noyori, R.
Tetrahedron Letters, 1987 , vol. 28, # 20 p. 2259 - 2262
反应条件
pyridine Hydrierung des Reaktionsprodukts an Palladium in wss.Aethanol und anschliessend Hydrolyse mit wss.H2SO4;
参考文献
Michelson; Todd
Journal of the Chemical Society, 1949 , p. 2476,2484