N-乙酰-L-苯丙氨酸甲酯合成路线 （共 84 条）
反应条件
potassium fluoride; triethylamine in N,N-dimethyl-formamide T=20°C; Acylation; Transacylation;
参考文献
Li, Wen-Ren; Chou, Hsueh-Hsuan
Synthesis, 2000 , # 1 p. 84 - 90
反应条件
potassium fluoride; triethylamine in N,N-dimethyl-formamide T=20°C; Acylation; Transacylation;
参考文献
Li, Wen-Ren; Chou, Hsueh-Hsuan
Synthesis, 2000 , # 1 p. 84 - 90
反应条件
potassium fluoride; triethylamine in N,N-dimethyl-formamide T=20°C; Acylation; Transacylation;
参考文献
Li, Wen-Ren; Chou, Hsueh-Hsuan
Synthesis, 2000 , # 1 p. 84 - 90
反应条件
1: (L)-phenylalanine methyl ester hydrochloride With p-nitrophenyl carbonate Merrifield resin; N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide T=20°C; Solid phase reaction; 6 h; 2: acetyl-bromide With triethylamine; zinc dibromide in dichloromethane T=20°C; Solid phase reaction;
参考文献
Li; Lin; Yo
Tetrahedron Letters, 2000 , vol. 41, # 34 p. 6619 - 6622
反应条件
1: Z-N-acetyl-a-aminocinnamic acid With hydrogen; [Rh(nbd)((Me3CCH2CMe2P(Me)CH2)2)]BF4 in methanol T=20°C; Catalytic hydrogenation; P=1520 Torr; 2 h; 2: diazomethyl-trimethyl-silane Esterification; Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 73, # 3 p. 705 - 712
反应条件
4-methyl-morpholine in methanol T=20°C; 24 h;
参考文献
Hioki, Kazuhito; Kameyama, Satomi; Tani, Shohei; Kunishima, Munetaka
Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 5 p. 825 - 828
反应条件
Aliquatreg; 336 in tetrahydrofuran T=-20°C; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 127, # 17 p. 6138 - 6139
反应条件
1: K2CO3 / dimethylformamide 2: H2 / [{(S)-1-(R)-b}Rh(COD)]BF4 / toluene / 2 h / 20 °C / 3.5 Torr View Scheme
参考文献
Organic Letters, , vol. 3, # 23 p. 3687 - 3690
反应条件
subtilisin Carlsberg protease in various solvent(s) 19 h;
参考文献
Saul, Simon; Corr, Stuart; Micklefield, Jason
Angewandte Chemie - International Edition, 2004 , vol. 43, # 41 p. 5519 - 5523
反应条件
KCl-Subtilisin Bacillus lentus in acetonitrile Ambient temperature;
参考文献
Lloyd, Richard C.; Dickman, Michael; Jones, J. Bryan
Tetrahedron Asymmetry, 1998 , vol. 9, # 4 p. 551 - 561
