potassium carbonate in N,N-dimethyl-formamide 2 h;

in hexane; dichloromethane T=0 - 20°C;

in methanol; toluene 16 h;

Pd/SrCO3; ethyl acetate T=150°C; P=110326 Torr; Hydrogenation;

1: aqueous sodium carbonate-solution; sodium-amalgam View Scheme

暂无反应条件数据

1: 2.0 g / pyridine / benzene / 24 h / 25 °C 2: 62.3 percent / 1,8-dizazabicyclo<5.4.0>undec-7-ene (DBU) / dioxane / 1 h / Heating 3: 63 percent / m-chloroperbenzoic acid (MCPBA) / CH2Cl2 / 2 h / 0 °C View Scheme

1.1: 90 percent / pyridinium chlorochromate; Celite; sodium carbonate / CH2Cl2 / 4 h / 20 °C 2.1: 90 percent / p-toluenesulfonic acid monohydrate / toluene / 18 h / Heating 3.1: 95 percent / LiAlH4 / diethyl ether / 3 h / 20 °C 4.1: 97 percent / oxalyl chloride; DMSO; triethylamine / CH2Cl2 / 2 h / -60 - 20 °C 5.1: sodium cyanide / ethanol / 2 h 5.2: 75 percent / NH3 / ethanol / 16 h / 90 - 110 °C 6.1: 94 percent / HCl / 1 h / 20 °C View Scheme

1: 82 percent / Celite(R); NaOAc; pyridinium chlorochromate / CH2Cl2 / 3.5 h 2: potassium carbonate / methanol / 20 °C View Scheme

1: 90 percent / pyridinium chlorochromate; Celite; sodium carbonate / CH2Cl2 / 4 h / 20 °C 2: 90 percent / p-toluenesulfonic acid monohydrate / toluene / 18 h / Heating View Scheme