4-O-(2,3,4,6-四-O-乙酰基)-β-D-吡喃(型)葡糖基-D-吡喃(型)葡糖四乙酸酯合成路线 （共 38 条）
反应条件
hydrogen bromide; acetic anhydride in acetic acid T=0 - 20°C; Substitution; 3 h;
参考文献
Allen; Zhang; Williams; Zatorski; Ragupathi; Livingston; Danischefsky
Chemistry - A European Journal, 2000 , vol. 6, # 8 p. 1366 - 1375
反应条件
1: Me3SiOTf / 1,2-dichloro-ethane View Scheme
参考文献
Kuyama, Hiroki; Nukada, Tomoo; Nakahara, Yoshiaki; Ogawa, Tomoya
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2171 - 2174
反应条件
1: 100 percent / HBr / acetic acid 2: TBAHS; aq. Na2CO3 / CH2Cl2 / 3 h / 20 °C View Scheme
参考文献
Giguere, Denis; Sato, Sachiko; St-Pierre, Christian; Sirois, Suzanne; Roy, Rene
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1668 - 1672
反应条件
1: 90.5 percent / SnCl4 / CH2Cl2 / 16 h / 20 °C 2: NaOMe / methanol / 16 h / 20 °C View Scheme
参考文献
Koike; Sugimoto; Sato; Ito; Nakahara; Ogawa
Carbohydrate research, 1987 , vol. 163, # 2 p. 189 - 208
反应条件
1: 63 percent / TMSOTf / 1,2-dichloro-ethane / 2 h 2: 97 percent / Et3N / methanol / 14 h / Heating View Scheme
参考文献
Kuyama, Hiroki; Nukada, Tomoo; Nakahara, Yoshiaki; Ogawa, Tomoya
Tetrahedron Letters, 1993 , vol. 34, # 13 p. 2171 - 2174
反应条件
1: TiBr4; glacial acetic acid / CH2Cl2 / 24 h / 20 °C
2: Zn/Cu; 1-methylimidazole; 4 Angstroem molecular sieves / CH2Cl2 / 12 h / Heating
View Scheme
参考文献
Shull, Brian K.; Wu, Zhijun; Koreeda, Masato
Journal of Carbohydrate Chemistry, 1996 , vol. 15, # 8 p. 955 - 964
反应条件
1: SnCl4; 4A molecular sieves / CH2Cl2 / 4 h / 20 °C
2: MeONa / methanol / Heating
View Scheme
参考文献
Droz, Anne Sophie; Neidlein, Ulf; Anderson, Sally; Seiler, Paul; Diederich, Francois
Helvetica Chimica Acta, 2001 , vol. 84, # 8 p. 2243 - 2289
反应条件
1: 75 percent / BF3*C2H5OC2H5 / CH2Cl2 / 24 h / 0 - 20 °C
2: NaOMe; IR resin (H+) / methanol
View Scheme
参考文献
Cheng, Janice M. H.; Dangerfield, Emma M.; Timmer, Mattie S. M.; Stocker, Bridget L.
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 17 p. 2729 - 2736
