N-叔丁氧羰基-L-金刚烷基甘氨酸合成路线 （共 11 条）
反应条件
1.1: 51 percent / KMnO4; aq. KOH / 1.5 h / 60 - 90 °C
2.1: 85 percent / EDAC; HOBT; TEA / dimethylformamide / 20 °C
3.1: pyridine; trifluoroacetic anhydride / tetrahydrofuran / 1 h
3.2: 92 percent / aq. KOH / methanol / 18 h / 20 °C
View Scheme
参考文献
Dong, Jizhe; Gong, Yanchun; Liu, Jun; Chen, Xiangfeng; Wen, Xiaoan; Sun, Hongbin
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1383 - 1393
