2-羟基乙基吡啶-3-羧酸酯合成路线 (共 6 条)
反应条件
triethylamine in dichloromethane T=20°C; 2 h;
参考文献
Qandil, Amjad M.; Rezigue, Meriem M.; Tashtoush, Bassam M.
European Journal of Pharmaceutical Sciences, 2011 , vol. 43, # 3 p. 99 - 108
参考文献
Vejdelek et al.
Chemicke Listy, 1952 , vol. 46, p. 423,426
Chem.Abstr., 1953 , p. 8068
反应条件
hydrogenchloride; water T=49.8°C; rate constant for hydrolysis, temperature and pH dependence; Rate constantProduct distribution;
参考文献
Garrett; Gardner
Journal of pharmaceutical sciences, 1982 , vol. 71, # 1 p. 14 - 25
反应条件
hydrogenchloride T=37°C; pH=7.4; aq. phosphate bufferEnzymatic reaction; Kinetics;
参考文献
Qandil, Amjad M.; Rezigue, Meriem M.; Tashtoush, Bassam M.
European Journal of Pharmaceutical Sciences, 2011 , vol. 43, # 3 p. 99 - 108
反应条件
Propylene glycol 0.116667 h; pharmacokinetics on intravenous infusion into dogs; other modes of administration, doses and formulations administered;
参考文献
Garrett; Altmayer
Journal of Pharmaceutical Sciences, 1985 , vol. 74, # 3 p. 295 - 299
反应条件
thionyl chloride; chloroform
参考文献
Vejdalek et al.
Collection of Czechoslovak Chemical Communications, 1954 , vol. 19, p. 1274,1280
Chem.Abstr., 1955 , p. 336