羟基-二苯基-乙酸 1-甲基-哌啶-4-基酯合成路线 （共 19 条）
反应条件
sodium methylate in n-heptane 15 h; Heating;
参考文献
Xu, Rong; Sim, Meng-Kwoon; Go, Mei-Lin
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 231 - 241
反应条件
ethanol; sodium ethanolate T=110 - 120°C; P=80 Torr;
参考文献
Farbw.Hoechst
Patent: DE959277 , 1952 ;
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Farbw.Hoechst
Patent: US2816895 , 1954 ;
反应条件
T=140 - 160°C; Erwaermen des Reaktionsprodukts in Wasser;
参考文献
Coan et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 3701
反应条件
MnTPFPPCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Frohlich; Pietzyk; Gober
Pharmazie, 1995 , vol. 50, # 11 p. 736 - 740
反应条件
MnTPFPPCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Frohlich; Pietzyk; Gober
Pharmazie, 1995 , vol. 50, # 11 p. 736 - 740
反应条件
MnTPFPPCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Frohlich; Pietzyk; Gober
Pharmazie, 1995 , vol. 50, # 11 p. 736 - 740
反应条件
MnTPFPPCl in methanol; dichloromethane T=20°C; 24 h; Further byproducts given;
参考文献
Frohlich; Pietzyk; Gober
Pharmazie, 1995 , vol. 50, # 11 p. 736 - 740
反应条件
1: NaHCO3 / dimethylformamide / 24 h / Ambient temperature 2: 25 percent / NaOMe / heptane / 15 h / Heating View Scheme
参考文献
Xu, Rong; Sim, Meng-Kwoon; Go, Mei-Lin
Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 2 p. 231 - 241
反应条件
1H-imidazole; dihydrogen peroxide; MnTPFPS4PCl in water T=20°C; 24 h; var. of pH, solvent, catalyst; Product distribution;
参考文献
Froehlich; Pietzyk; Smolinka; Goeber
Pharmazie, 1996 , vol. 51, # 10 p. 745 - 747
反应条件
in acetonitrile 15 h; Ambient temperature; Yield given;
参考文献
Sugai; Hasegawa; Yoshida; Akaboshi
Chemical and Pharmaceutical Bulletin, 1984 , vol. 32, # 3 p. 977 - 985
