6-氨基吡啶-2-羧酸甲酯合成路线

MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank
Patent: WO2013/52394 A1, 2013 ;
Location in patent: Paragraph 00209 ;

36052-26-36-氨基吡啶-2-羧酸甲酯

178876-83-06-氨基-3-溴吡啶-2-甲酸甲酯+

178876-82-95-溴-6-氨基吡啶-2-羧酸甲酯

参考文献

Journal of Organic Chemistry, , vol. 61, # 14 p. 4623 - 4633

36052-26-36-氨基吡啶-2-羧酸甲酯

178876-82-95-溴-6-氨基吡啶-2-羧酸甲酯

参考文献

Ontoria, Jesus M.; Martin Hernando, Jose I.; Malancona, Savina; Attenni, Barbara; Stansfield, Ian; Conte, Immacolata; Ercolani, Caterina; Habermann, Joerg; Ponzi, Simona; Di Filippo, Marcello; Koch, Uwe; Rowley, Michael; Narjes, Frank
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 15 p. 4026 - 4030

36052-26-36-氨基吡啶-2-羧酸甲酯

443956-21-66-氨基-3,5-二溴吡啶甲酸甲酯+

178876-83-06-氨基-3-溴吡啶-2-甲酸甲酯+

178876-82-95-溴-6-氨基吡啶-2-羧酸甲酯

参考文献

WO2011/75591 A1, ;

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