甲基-D-半乳糖苷-2,3,6-三苯甲酸酯合成路线 （共 13 条）
反应条件
pyridine T=9 - 18°C; Large scale reaction;
参考文献
Organic Process Research and Development, , vol. 14, # 3 p. 623 - 631
反应条件
tert.-butylhydroperoxide; copper dichloride in benzene T=50°C; 15 h; Yield given. Yields of byproduct given;
参考文献
Chemistry Letters, , # 10 p. 1699 - 1702
反应条件
1: α-D-GalOMe With di(n-butyl)tin oxide in toluene; benzene Heating; 2: benzoyl chloride in toluene T=45°C; 2.5 h;
参考文献
Tetrahedron, , vol. 58, # 32 p. 6513 - 6519
反应条件
1: 100 percent / imidazole / dimethylformamide / 20 °C 2: 80 percent / TBAF / tetrahydrofuran / 0 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 23 p. 3857 - 3860
参考文献
European Journal of Organic Chemistry, , # 10 p. 1592 - 1597
反应条件
bis(tri-n-butyltin)oxide 1.) toluene, 2.) toluene, 20 deg C, 24 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 37, p. 2363 - 2370
反应条件
[bis(2-methoxyethyl)amino]-sulfur trifluoride in tetrahydrofuran T=20 - 52°C; Large scale reaction;
参考文献
Weiberth, Franz J.; Gill, Harpal S.; Jiang, Ying; Lee, George E.; Lienard, Philippe; Pemberton, Clive; Powers, Matthew R.; Subotkowski, Witold; Tomasik, Witold; Vanasse, Benoit J.; Yu, Yong
Organic Process Research and Development, 2010 , vol. 14, # 3 p. 623 - 631
反应条件
pyridine in dichloromethane 0.75 h; -20 degC, then allowed to warm to room temperature;
参考文献
Reed, Lawrence A.; Goodman, Leon
Carbohydrate Research, 1981 , vol. 94, p. 91 - 100
反应条件
1: 50.5 percent / DAST / CH2Cl2 2: 65.9 percent / NaOMe / methanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 23 p. 6994 - 6998
反应条件
1: 56 percent / diethylaminosulfur trifluoride, 4-(dimethylamino)pyridine / CH2Cl2 / 1) -20 deg C, 15 min, 2) RT, 24 h
2: 78 percent / 1M NaOMe in MeOH / 18 h / Ambient temperature
3: H2O, Dowex 50W-X8<H(1+)> / 25 h / Heating
View Scheme
参考文献
Withers, Stephen G.; MacLennan, David J.; Street, Ian P.
Carbohydrate Research, 1986 , vol. 154, p. 127 - 144
