1.1: triethylamine / dichloromethane / 15 h / 20 °C / |Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / |Inert atmosphere
2.2: 15 h / 0 - 20 °C / |Inert atmosphere
3.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / |Inert atmosphere
3.2: 16 h / 20 °C / |Inert atmosphere
View Scheme
参考文献
Fournier, Anne M.; Nichols, Christopher J.; Vincent, Mark A.; Hillier, Ian H.; Clayden, Jonathan
Chemistry - A European Journal, 2012 , vol. 18, # 51 p. 16478 - 16490
1.1: triethylamine / dichloromethane / 15 h / 20 °C / |Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C / |Inert atmosphere
2.2: 15 h / 0 - 20 °C / |Inert atmosphere
3.1: sec.-butyllithium / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere
View Scheme
参考文献
Fournier, Anne M.; Nichols, Christopher J.; Vincent, Mark A.; Hillier, Ian H.; Clayden, Jonathan
Chemistry - A European Journal, 2012 , vol. 18, # 51 p. 16478 - 16490