2-氨基-1-(2,5-二甲氧基苯基)乙醇合成路线 (共 6 条)
反应条件
hydrogenchloride; borane in tetrahydrofuran
参考文献
Synaptic Pharmaceutical Corporation
Patent: US5610174 A1, 1997 ;
US 5610174 A
反应条件
lithium aluminium tetrahydride in diethyl ether 1 h; Heating;
参考文献
Perez; Rosell; Mauleon; Carganico
Farmaco, 1991 , vol. 46, # 10 p. 1155 - 1166
反应条件
ammonia in ethanol 120 h; Ambient temperature;
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 254 - 259
反应条件
1: NaBH4 / dioxane; H2O / 1 h / Ambient temperature 2: KOH / diethyl ether; H2O / 0.5 h / Heating 3: NH3 / ethanol / 120 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 2 p. 254 - 259
反应条件
1: 90 percent / zinc iodide / 1 h / Ambient temperature 2: 54 percent / lithium aluminum hydride / diethyl ether / 1 h / Heating View Scheme
参考文献
Farmaco, , vol. 46, # 10 p. 1155 - 1166
反应条件
sodium hydroxide in dichloromethane; water
4 h; Ambient temperature;
参考文献
Epifani, E.; Lapucci, A.; Macchia, B.; Macchia, F.; Tognetti, P.; et al.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 254 - 259