N-(苄氧羰基)-L-苯丙氨酸甲酯合成路线 （共 61 条）
反应条件
4 A molecular sieve in diethyl ether T=-60°C; 17 h; Title compound not separated from byproducts.;
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
参考文献
Shibuya, Masatoshi; Sato, Takahisa; Tomizawa, Masaki; Iwabuchi, Yoshiharu
Chemical Communications, 2009 , # 13 p. 1739 - 1741
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran 0.5 h;
参考文献
Takeda; Akiyama; Nakamura; Takizawa; Mizuno; Takayanagi; Harigaya
Synthesis, 1994 , # 10 p. 1063 - 1066
反应条件
sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran Ambient temperature;
参考文献
Beugelmans, Rene; Neuville, Luc; Bois-Choussy, Michele; Chastanet, Jacqueline; Zhu, Jieping
Tetrahedron Letters, 1995 , vol. 36, # 18 p. 3129 - 3132
反应条件
1: tetrahydrofuran / 50 °C 2: NMM / tetrahydrofuran / -25 - 20 °C 3: 10 mol percent (DHQD)2AQN; 4 Angstroem molecular sieves / diethyl ether / 17 h / -60 °C View Scheme
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
1: NMM / tetrahydrofuran / -25 - 20 °C 2: 10 mol percent (DHQD)2AQN; 4 Angstroem molecular sieves / diethyl ether / 17 h / -60 °C View Scheme
参考文献
Hang; Tian; Tang; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12696 - 12697
反应条件
1: pyridine / acetonitrile / 1 h / Ambient temperature 2: pyridine / acetonitrile / 8 h / Ambient temperature View Scheme
参考文献
Pinho, Vagner D.; Gutmann, Bernhard; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.; Kappe, C. Oliver
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1555 - 1562
反应条件
trifluorormethanesulfonic acid in cyclohexane 1 h;
参考文献
Barrett, Anthony G. M.; Pilipauskas, Daniel
Journal of Organic Chemistry, 1990 , vol. 55, # 17 p. 5170 - 5173
反应条件
cross-linked enzyme aggregates of Alcalase T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Cusan, Claudia; Van Dooren, Theodorus J. G. M.; Moody, Harold M.; Merkx, Remco; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2399 - 2404
反应条件
alcalase cross-linked enzyme aggregates T=50°C; 48 h; Molecular sieveEnzymatic reaction;
参考文献
Nuijens, Timo; Piva, Elena; Kruijtzer, John A. W.; Rijkers, Dirk T. S.; Liskamp, Rob M. J.; Quaedflieg, Peter J. L. M.
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 7 p. 1039 - 1044
