N-(苄氧羰基)-L-苯丙氨酸甲酯合成路线 (共 61 条)
反应条件
sodium carbonate in water; ethyl acetate T=0 - 16°C;
参考文献
Sun, Dequn; Zhang, Lingzi; Wang, Jin
Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322
反应条件
yttria-zirconia based Lewis acid catalyst in acetonitrile T=20°C; 0.3 h;
参考文献
Pandey, Rajesh K.; Dagade, Sharda P.; Dongare, Mohan K.; Kumar, Pradeep
Synthetic Communications, 2003 , vol. 33, # 23 p. 4019 - 4027
反应条件
chloro-trimethyl-silane 18 h;
参考文献
Edmonds; Abell
Journal of Organic Chemistry, 2001 , vol. 66, # 11 p. 3747 - 3752
反应条件
hydrogen; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; ethylenediamine T=20°C; Hydrogenolysis; esterification; P=760 Torr; 14 h;
参考文献
Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 2000 , vol. 56, # 43 p. 8433 - 8441
反应条件
DMT*brucine tetrafluoroborate; (-)-Brucine in acetonitrile T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Kolesinska, Beata; Kaminski, Zbigniew J.
Organic Letters, 2009 , vol. 11, # 3 p. 765 - 768
反应条件
in tetrahydrofuran; hexane
参考文献
Suntory Limited
Patent: US4837349 A1, 1989 ;
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=0°C; 1 h;
参考文献
Sakaitani, Masahiro; Ohfune, Yasufumi
Journal of Organic Chemistry, 1990 , vol. 55, # 3 p. 870 - 876
反应条件
potassium hydrogencarbonate; sodium sulfite in water; N,N-dimethyl-formamide
参考文献
Welfide Corporation
Patent: US6528514 B1, 2003 ;
反应条件
1: methanol; L-phenylalanine With water; sodium hydrogencarbonate 0.166667 h; 2: benzyl chloroformate in water Product distribution / selectivity;
参考文献
THE UNIVERSITY OF MANITOBA
Patent: WO2006/96994 A1, 2006 ;
Location in patent: Page/Page column 8 ;
反应条件
S(+)-2,3-O,N-bis(diphenylphosphino)-1-(-naphthoxy)-2-hydroxy-3-isopropylaminopropane; Rh(cyclo-octa-1,5-diene)2; hydrogen; tetrafluoroboric acid in methanol T=25°C; P=750.06 Torr; other (Z)-acylaminocinnamic acid derivatives; other chiral ligands; Product distribution;
参考文献
Evans, David A.; Michael, Forrest E.; Tedrow, Jason S.; Campos, Kevin R.
Journal of the American Chemical Society, 2003 , vol. 125, # 12 p. 3534 - 3543