2,3,4,5-四甲氧基甲苯合成路线 （共 45 条）
反应条件
sodium methylate 1.) methanol, DME, dimethyl carbonate, 80 deg C, 5 h 2.) methanol, DME, water, RT, 2 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 52, # 17 p. 3872 - 3875
反应条件
n-butyllithium 1.) Et2O, 30 min, 2.) Et2O, 1 h, low temperature, 10 h, room temperature, 3 h, reflux; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 36, # 1 p. 123 - 129
反应条件
1: HCl 2: 88 percent / Ni(PPh3)4 / tetrahydrofuran / 20 °C 3: 60 percent / Ce(NH4)2(NO3)6 / CH2Cl2; H2O; acetonitrile View Scheme
参考文献
Lipshutz, Bruce H.; Bulow, Gerd; Fernandez-Lazaro, Fernando; Kim, Sung-Kyu; Lowe, Richard; Mollard, Paul; Stevens, Kirk L.
Journal of the American Chemical Society, 1999 , vol. 121, # 50 p. 11664 - 11673
反应条件
pyridine-2,6-dicarboxylic acid; ammonium cerium(IV) nitrate in water; acetonitrile a.) 20 min, 0 deg C b.) 10 min, RT;
参考文献
Keinan, Ehud; Eren, Doron
Journal of Organic Chemistry, 1987 , vol. 52, # 17 p. 3872 - 3875
反应条件
bromine in dichloromethane T=3 - 5°C; 0.0833333 h;
参考文献
Organic and Biomolecular Chemistry, , vol. 2, # 16 p. 2371 - 2375
反应条件
anhydrous iron chloride in dichloromethane
T=40°C; Friedel-Crafts Alkylation; 8 h; Overall yield = 67 percent; Overall yield = 1.16 g;
参考文献
Lee, Sang Who; Lee, Hee Bong; Kim, Bong Chan; Sadaiah, Kadivendi; Lee, Kyuwoong; Shin, Hyunik
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1257 - 1259
反应条件
montmollironite K-10 in neat (no solvent)
T=80°C; Friedel-Crafts Alkylation; 16 h; Time; stereoselective reaction;
参考文献
Lee, Sang Who; Lee, Hee Bong; Kim, Bong Chan; Sadaiah, Kadivendi; Lee, Kyuwoong; Shin, Hyunik
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1257 - 1259
反应条件
tin(IV) chloride in 1,2-dichloro-ethane
T=80°C; Friedel-Crafts reaction; 8 h; Product distribution; Further Variations:ReagentsSolventsTemperaturesreaction times;
参考文献
Min, Jae-Hong; Lee, Jun-Sup; Yang, Jae-Deuk; Koo, Sangho
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7925 - 7927
反应条件
tin(IV) chloride in 1,2-dichloro-ethane
T=80°C; Friedel-Crafts reaction; 8 h; Product distribution; Further Variations:ReagentsSolventsTemperaturesreaction times;
参考文献
Min, Jae-Hong; Lee, Jun-Sup; Yang, Jae-Deuk; Koo, Sangho
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7925 - 7927
反应条件
aluminium trichloride in dichloromethane
参考文献
Jung, Young-Sik; Joe, Bo-Young; Cho, Sung Ju; Konishi, Yasuo
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 4 p. 1125 - 1129
