6-甲氧基-1-甲基-9H-吡啶并(3,4-b)吲哚合成路线 （共 9 条）
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in toluene 3 h; Heating;
参考文献
Sapi, Janos; Patigny, Dominique; Laronze, Jean-Yves
Heterocycles, 1999 , vol. 51, # 2 p. 361 - 364
反应条件
1: methanol; water / 12 h / 20 °C 2: HCl / 100 °C 3: cumene / Pd/C / Heating View Scheme
参考文献
Sapi, Janos; Patigny, Dominique; Laronze, Jean-Yves
Heterocycles, 1999 , vol. 51, # 2 p. 361 - 364
反应条件
1: HCl / 100 °C 2: cumene / Pd/C / Heating View Scheme
参考文献
Schott, Yvonne; Decker, Michael; Rommelspacher, Hans; Lehmann, Jochen
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5840 - 5843
反应条件
palladium T=190 - 200°C;
参考文献
Spaeth; Lederer
Chemische Berichte, 1930 , vol. 63, p. 2102,2106
反应条件
1: hydrogenchloride / methanol / 20 °C 2: manganese(IV) oxide; 5 Pd(II)/C(eggshell) / N,N-dimethyl-formamide / 150 °C / Microwave irradiation View Scheme
参考文献
Cuny, Gregory D.; Ulyanova, Natalia P.; Patnaik, Debasis; Liu, Ji-Feng; Lin, Xiangjie; Auerbach, Ken; Ray, Soumya S.; Xian, Jun; Glicksman, Marcie A.; Stein, Ross L.; Higgins, Jonathan M.G.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 2015 - 2019
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C 2: hydrogenchloride / methanol / 20 °C 3: manganese(IV) oxide; 5 Pd(II)/C(eggshell) / N,N-dimethyl-formamide / 150 °C / Microwave irradiation View Scheme
参考文献
Cuny, Gregory D.; Ulyanova, Natalia P.; Patnaik, Debasis; Liu, Ji-Feng; Lin, Xiangjie; Auerbach, Ken; Ray, Soumya S.; Xian, Jun; Glicksman, Marcie A.; Stein, Ross L.; Higgins, Jonathan M.G.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 2015 - 2019
反应条件
1: aq. H2SO4 / 12 h / 65 °C 2: K2Cr2O7; aq. AcOH / 0.05 h / Heating View Scheme
参考文献
Song, Yongcheng; Wang, Jian; Teng, Su Fern; Kesuma, Djohan; Deng, Yu; Duan, Jinao; Wang, Jerry H.; Qi, Robert Zhong; Sim, Mui Mui
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 7 p. 1129 - 1132
反应条件
1: PCl5; xylene 2: palladium powder / 190 - 200 °C View Scheme
参考文献
Spaeth; Lederer
Chemische Berichte, 1930 , vol. 63, p. 2102,2106
反应条件
hydrogen bromide; acetic acid
T=130°C;
参考文献
Schott, Yvonne; Decker, Michael; Rommelspacher, Hans; Lehmann, Jochen
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 22 p. 5840 - 5843
