5-氯-2-(三氯甲基)苯并咪唑合成路线 （共 3 条）
反应条件
acetic acid T=20°C; 1.16667 h; Cooling;
参考文献
Zhang, Lei; Chen, Xiaojie; Liu, Jun; Zhu, Qingzhang; Leng, Ying; Luo, Xiaomin; Jiang, Hualiang; Liu, Hong
European Journal of Medicinal Chemistry, 2012 , vol. 58, p. 624 - 639
反应条件
1: hydrogenchloride; iron / ethanol; water / Reflux 2: acetic acid / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 1156 - 1159
反应条件
1: With sodium hydroxide; water T=0°C; 1 h; 2: With hydrogenchloride in water pH=3; 1 h;
参考文献
MERCK PATENT GmbH
Patent: WO2005/4863 A1, 2005 ;
Location in patent: Page/Page column 135 ;
WO 2005/004863 A1
