4-甲基-2,6-二氧代-[1,3]噁嗪烷-3-羧酸叔丁酯合成路线 （共 4 条）
反应条件
pyridine; oxalyl dichloride; N,N-dimethyl-formamide in acetonitrile T=-20 - 20°C; 7 h;
参考文献
McKiernan; Huck; Fehrentz; Roumestant; Viallefont; Martinez
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6541 - 6544
反应条件
1.1: Cs2CO3 / methanol; H2O 1.2: 91 percent / dimethylformamide / 22 h 2.1: 60 percent / DMAP / acetonitrile / 24 h / 20 °C 3.1: 82 percent / H2 / 10percent palladium hydroxide on carbon / methanol / 2 h / 20 °C 4.1: 62 percent / DMF; oxalyl chloride; pyridine / acetonitrile / 7 h / -20 - 20 °C View Scheme
参考文献
McKiernan; Huck; Fehrentz; Roumestant; Viallefont; Martinez
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6541 - 6544
反应条件
1: 60 percent / DMAP / acetonitrile / 24 h / 20 °C 2: 82 percent / H2 / 10percent palladium hydroxide on carbon / methanol / 2 h / 20 °C 3: 62 percent / DMF; oxalyl chloride; pyridine / acetonitrile / 7 h / -20 - 20 °C View Scheme
参考文献
McKiernan; Huck; Fehrentz; Roumestant; Viallefont; Martinez
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6541 - 6544
反应条件
1: 82 percent / H2 / 10percent palladium hydroxide on carbon / methanol / 2 h / 20 °C 2: 62 percent / DMF; oxalyl chloride; pyridine / acetonitrile / 7 h / -20 - 20 °C View Scheme
参考文献
McKiernan; Huck; Fehrentz; Roumestant; Viallefont; Martinez
Journal of Organic Chemistry, 2001 , vol. 66, # 20 p. 6541 - 6544
