1.1: 92 percent / NaI / acetone / 20 °C 2.1: CH2Cl2 / 0.5 h / 20 °C 3.1: CH2Cl2 / 0.5 h / 20 °C 4.1: LDA / tetrahydrofuran / 0.5 h / -78 °C 4.2: tetrahydrofuran / 1.5 h / -30 °C 5.1: 59 mg / DDQ / tetrahydrofuran; methanol / 4 h / 20 °C 6.1: 60 percent / AIBN; TTMSS / benzene / 4 h / Heating 7.1: DIBAL / CH2Cl2 / 0.75 h / -78 - -30 °C 7.2: 45 percent / NaBH4 / methanol; CH2Cl2 / 1 h / 0 °C 8.1: 60 percent / I2; CaCO3 / methanol; H2O / 96 h / 20 °C View Scheme

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 50 °C / Inert atmosphere 2: palladium diacetate; potassium carbonate; triphenylphosphine / toluene / 16 h / Reflux; Inert atmosphere View Scheme

ammonium hydroxide T=20°C; 120 h;

potassium tert-butylate in N,N-dimethyl-formamide T=20°C; 1.5 h;

1: 91 percent / aq. NH4OH / 120 h / 20 °C 2: 82 percent / MgSO4 / diethyl ether / 10 h / 20 °C 3: 84 percent / Et3N / CH2Cl2 / 0.5 h / 20 °C 4: 85 percent / Bu3SnH; AIBN / benzene / 4 h / Heating 5: NaBH4 / ethanol / 0.5 h / 20 °C 6: 415.1 mg / EDC / CH2Cl2 / 16 h / 20 °C 7: 98 percent / MCPBA / CH2Cl2 / 0.5 h / 0 °C 8: 63 percent / CaCO3 / toluene / 13 h / Heating 9: methanol / 1.5 h / 20 °C / Irradiation 10: 2.8 mg / Pd/C / acetic acid / 3 h / 80 °C View Scheme