(R)-2-甲基-4-苯甲酰基哌嗪合成路线

参考文献

AMGEN INC.
Patent: WO2009/35568 A1, 2009 ;
Location in patent: Page/Page column 69 ;
WO 2009/035568 A1

参考文献

Wang, Jingsong; Le, Nhut; Heredia, Alonso; Song, Haijing; Redfield, Robert; Wang, Lai-Xi
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 9 p. 1781 - 1786

474010-60-1(R)-1-苯甲酰基-3-甲基哌嗪盐酸盐

357263-39-9(R)-2-甲基-4-苯甲酰基哌嗪

参考文献

PFIZER LIMITED
Patent: WO2006/85199 A1, 2006 ;
Location in patent: Page/Page column 22; 23 ;
WO 2006/085199 A1

357263-39-9(R)-2-甲基-4-苯甲酰基哌嗪

357263-13-9BMS 378806; 1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-b]吡啶-3-基)-1,2-乙二酮

参考文献

Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

357263-39-9(R)-2-甲基-4-苯甲酰基哌嗪

357262-90-94-苯甲酰基-2-甲基-1-[(7-氧化-1H-吡咯并[2,3-b]吡啶)氧代乙酰基]-哌嗪

参考文献

Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239