5-(吡啶-3-基)-4H-1,2,4-三唑-3-胺合成路线 （共 7 条）
反应条件
1: With sodium hydroxide in water T=20°C; 2: T=230°C;
参考文献
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
Patent: WO2008/117943 A1, 2008 ;
Location in patent: Page/Page column 14 ;
反应条件
1: With sulfuric acid in water T=140°C; 72 h; 2: With potassium carbonate in water
参考文献
VERSEON, INC.; SHORT, Kevin, Michael; PHAM, Son, Minh; WILLIAMS, David, Charles; DATTA, Somalee
Patent: WO2011/126903 A2, 2011 ;
Location in patent: Page/Page column 66 ;
WO 2011/126903 A2
反应条件
in water 0.0416667 h; Microwave irradiation;
参考文献
Dolzhenko, Anton V.; Pastorin, Giorgia; Dolzhenko, Anna V.; Chui, Wai Keung
Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2124 - 2128
反应条件
1: NaOH / H2O / 20 h / 23 °C 2: 0.5 h / 250 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 26, # 1 p. 1 - 6
反应条件
sodium hydroxide in water T=100°C;
参考文献
Chernyshev; Tarasova; Chernysheva; Taranushich
Russian Journal of Applied Chemistry, 2011 , vol. 84, # 11 p. 1890 - 1896
参考文献
Abdel-Hafez, Atef A.; Elsherief, Hosny A. H.; Jo, Michiko; Kurokawa, Masahiko; Shiraki, Kimiyasu; Kawahata, Takuya; Otake, Toru; Nakamura, Norio; Hattori, Masao
Arzneimittel-Forschung/Drug Research, 2002 , vol. 52, # 11 p. 833 - 839
反应条件
1: hydrogenchloride / water / 180 - 185 °C / Reflux 2: sodium hydroxide / water / 100 °C View Scheme
参考文献
Russian Journal of Applied Chemistry, , vol. 84, # 11 p. 1890 - 1896
