6-氯恶唑并[4,5-b]吡啶-2(3H)-酮合成路线 （共 10 条）
反应条件
pyridine in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; chloroform
参考文献
Ciba-Geigy Corporation
Patent: US4033975 A1, 1977 ;
反应条件
in acetonitrile T=85°C;
参考文献
WO2007/22257 A2, ;
Page/Page column 79 ;
WO 2007/022257 A2
反应条件
chlorine in N,N-dimethyl-formamide Ambient temperature;
参考文献
Helvetica Chimica Acta, , vol. 59, p. 1593 - 1612
反应条件
1: Py / 1 h / Ambient temperature 2: Cl2 / dimethylformamide / Ambient temperature View Scheme
参考文献
Helvetica Chimica Acta, , vol. 59, p. 1593 - 1612
反应条件
in toluene 24 h; Heating;
参考文献
Hisano, Takuzo; Harano, Kazunobu; Fukuoka, Ryuichi; Matsuoka, Toshikazu; Muraoka, Keiji; Shinohara, Ikuo
Chemical and Pharmaceutical Bulletin, 1986 , vol. 34, # 4 p. 1485 - 1492
反应条件
1: H2O 2: SOCl2 / CHCl3 3: methanol / 0.08 h / Heating View Scheme
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
反应条件
hydrogenchloride; formaldehyd in water
参考文献
Ciba-Geigy Corporation
Patent: US4033975 A1, 1977 ;
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
反应条件
1: H2O 2: SOCl2 / CHCl3 3: acetone / 4 h / 35 °C View Scheme
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
反应条件
1: H2O
2: SOCl2 / CHCl3
3: methanol / 0.13 h / Heating
View Scheme
参考文献
Ruefenacht,K. et al.
Helvetica Chimica Acta, 1976 , vol. 59, p. 1593 - 1612
