3-甲氧基-4-甲基苯甲酸甲酯合成路线 （共 27 条）
反应条件
sodium hydroxide in water T=20 - 55°C; pH=8.2 - 11.8; 8 h;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2009/191183 A1, 2009 ;
Location in patent: Page/Page column 51 ;
参考文献
ICI Americas Inc.
Patent: US5047402 A1, 1991 ;
反应条件
copper(l) iodide in methanol; N,N-dimethyl-formamide T=90°C; 3 h;
参考文献
Sengupta, Sujaya; Drew, Michael G. B.; Mukhopadhyay, Ranjan; Achari, Basudeb; Banerjee, Asish Kr
Journal of Organic Chemistry, 2005 , vol. 70, # 19 p. 7694 - 7700
反应条件
potassium carbonate in N,N-dimethyl-formamide 19 h; Heating;
参考文献
Dawson, Marcia I.; Chan, Rebecca; Hobbs, Peter D.; Chao, Wan-ru; Schiff, Leonard J.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 9 p. 1282 - 1293
反应条件
hydrogenchloride; sulfuric acid; potassium carbonate; dimethyl sulfate; sodium nitrite in methanol; water; acetone
参考文献
US5409928 A1, ;
US 5409928 A
反应条件
methyl iodide in water; N,N-dimethyl-formamide
反应条件
acetic acid in diethyl ether
参考文献
Irie; Matsumoto; Nishimura; Zhang
Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1852 - 1856
反应条件
acetyl chloride 36 h;
参考文献
Goverdhan, Gilla; Reddy, Anumula Raghupathi; Sampath, Aalla; Srinivas, Kurella; Himabindu, Vurimidi; Reddy, Ghanta Mahesh
Organic Process Research and Development, 2009 , vol. 13, # 1 p. 67 - 72
反应条件
in methanol; ethyl acetate
反应条件
in ethyl acetate; acetone
参考文献
Duke University
Patent: US6127356 A1, 2000 ;
