噻吩-2-硼酸新戊二醇酯合成路线 （共 14 条）
反应条件
1: thien-2-yl bromide With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tBuCH2CH2B(H)NiPr2; triethylamine; triphenylphosphine in tetrahydrofuran T=65°C; Alcaraz-Vaultier borylation; 12 h; Inert atmosphere; 2: 3-hydroxy-2,2-dimethylpropanol in tetrahydrofuran T=0 - 25°C; 0.25 h; Inert atmosphere; Further stages;
参考文献
Tetrahedron, , vol. 67, # 3 p. 576 - 583
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; [1,3-bis(diphenylphosphino) propane] dichloronickel(II); triethylamine in toluene T=23 - 100°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 75, # 16 p. 5438 - 5452
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran; hexane T=-40°C; 1 h; 2: With tributoxyborane in tetrahydrofuran; hexane T=-90°C; 1 h; 3: 3-hydroxy-2,2-dimethylpropanol in tetrahydrofuran; hexane T=20°C; 0.25 h; Further stages.;
参考文献
European Journal of Organic Chemistry, , # 15 p. 2799 - 2812
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II); 1,3-bis-(diphenylphosphino)propane; triethylamine in toluene T=23 - 100°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 75, # 16 p. 5438 - 5452
参考文献
Journal of the American Chemical Society, , vol. 129, # 19 p. 6098 - 6099
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; [1,3-bis(diphenylphosphino) propane] dichloronickel(II); triethylamine; zinc in toluene T=100°C; 7 h; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 75, # 22 p. 7822 - 7828
反应条件
[1,3-bis(diphenylphosphino) propane] dichloronickel(II); triphenylphosphine; zinc T=100°C; Inert atmosphere;
参考文献
Journal of Organic Chemistry, , vol. 76, # 24 p. 9946 - 9955
反应条件
1: With potassium tert-butylate; silver(I) acetate; triphenylphosphine in tetrahydrofuran T=70°C; P=15201 Torr; 16 h; Inert atmosphereAutoclave; 2: With hydrogenchloride in tetrahydrofuran; water Inert atmosphere;
参考文献
Zhang, Xiao; Zhang, Wen-Zhen; Shi, Ling-Long; Guo, Chun-Xiao; Zhang, Ling-Ling; Lu, Xiao-Bing
Chemical Communications, 2012 , vol. 48, # 50 p. 6292 - 6294
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 12 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Resmerita, Ana-Maria; Rosen, Brad M.; Percec, Virgil
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 9946 - 9955
反应条件
bis(1,5-cyclooctadiene)nickel (0); potassium phosphate; tri-cyclo-hexyl-phosphine in tetrahydrofuran T=25°C; 12 h; Inert atmosphere;
参考文献
Leowanawat, Pawaret; Zhang, Na; Resmerita, Ana-Maria; Rosen, Brad M.; Percec, Virgil
Journal of Organic Chemistry, 2011 , vol. 76, # 24 p. 9946 - 9955
