3-乙基-4-甲基呋喃-2,5-二酮合成路线 （共 12 条）
反应条件
copper(l) iodide in N,N,N',N',N'',N''-hexamethylphosphoric triamide; diethyl ether T=-5 - 20°C; 8 h;
参考文献
Deshpande, Anil M.; Natu, Arvind A.; Argade, Narshinha P.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9557 - 9558
反应条件
1: With sodium nitrate in dichloromethane; water T=45°C; 17 h; 2: With sulfuric acid; water; acetic acid T=140°C; 65 h;
参考文献
Pattarozzi, Mariella; Ghelfi, Franco; Roncaglia, Fabrizio; Pagnoni, Ugo M.; Parsonsb, Andrew F.
Synlett, 2009 , # 13 p. 2172 - 2176
反应条件
1: 60 percent / NBS, benzoyl peroxide / CCl4 / 10 h / Heating 2: CuI / diethyl ether; hexamethylphosphoric acid triamide / 8 h / -5 - 20 °C View Scheme
参考文献
Deshpande, Anil M.; Natu, Arvind A.; Argade, Narshinha P.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9557 - 9558
反应条件
potassium cyanide anschliessendes Erwaermen mit konz. wss. Salzsaeure;
参考文献
Muir; Neuberger
Biochemical Journal, 1949 , vol. 45, p. 163,165
反应条件
sodium hydrogensulfite anschliessend mit Natriumcyanid und Erwaermen des Reaktionsprodukts mit konz. wss. Salzsaeure;
参考文献
Skwartschenko et al.
Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 1784,1786; engl. Ausg. S. 1851, 1853
反应条件
hydrogenchloride; N,N,N',N,-tetramethylethylenediamine; lithium diisopropyl amide 1.) THF, 0 deg C, 3 h, 2.) H2O, 150 deg C, 0.1 Hgmm; Yield given. Multistep reaction;
参考文献
Mahidol, Chulabhorn; Pinyopronpanit, Yongyut; Radviroongit, Shuleewan; Thebtaranonth, Chachanat; Thebtaranonth, Yodhathai
Journal of the Chemical Society, Chemical Communications, 1988 , # 20 p. 1382 - 1383
反应条件
silica gel 1.) CH2Cl2, 10-15 deg C, irradiation, 30 min, 2.) EtOAc, hexane; Yield given. Multistep reaction;
参考文献
Poigny, Stephane; Guyot, Michele; Samadi, Mohammad
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 15 p. 2175 - 2177
反应条件
T=100°C; im geschlossenen Rohr; anhydride of/the/ low-melting α-methyl-α'-ethyl-succinic acid;
参考文献
Bischoff
Chemische Berichte, 1890 , vol. 23, p. 3422
参考文献
Biochemical Journal, , vol. 45, p. 163,165
参考文献
Justus Liebigs Annalen der Chemie, , vol. 345, p. 14
