5-(二氨基亚甲基氨基)-2-[[8-[[14-羟基-10,13-二甲基-17-(6-氧代吡喃-3-基)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-十四氢环戊烯并[a]菲-3-基]氧基]-8-氧代辛酰]氨基]戊酸合成路线 （共 3 条）
→
35455-33-55-(二氨基亚甲基氨基)-2-[[8-[[14-羟基-10,13-二甲基-17-(6-氧代吡喃-3-基)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-十四氢环戊烯并[a]菲-3-基]氧基]-8-氧代辛酰]氨基]戊酸
反应条件
1: 0.125 g / pyridine / 6 h / Heating 2: 1.) triethylamine, 2.) isobutyl chloroformate View Scheme
参考文献
Pettit, George R.; Kamano, Yoshiaki; Drasar, Pavel; Inoue, Masuo; Knight, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3573 - 3578
→
35455-33-55-(二氨基亚甲基氨基)-2-[[8-[[14-羟基-10,13-二甲基-17-(6-氧代吡喃-3-基)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-十四氢环戊烯并[a]菲-3-基]氧基]-8-氧代辛酰]氨基]戊酸
反应条件
1: 0.125 g / pyridine / 6 h / Heating 2: 1.) triethylamine, 2.) isobutyl chloroformate View Scheme
参考文献
Pettit, George R.; Kamano, Yoshiaki; Drasar, Pavel; Inoue, Masuo; Knight, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3573 - 3578
→
35455-33-55-(二氨基亚甲基氨基)-2-[[8-[[14-羟基-10,13-二甲基-17-(6-氧代吡喃-3-基)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-十四氢环戊烯并[a]菲-3-基]氧基]-8-氧代辛酰]氨基]戊酸
反应条件
triethylamine; isobutyl chloroformate Yield given. Multistep reaction;
参考文献
Pettit, George R.; Kamano, Yoshiaki; Drasar, Pavel; Inoue, Masuo; Knight, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 16 p. 3573 - 3578
