5-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯合成路线

FRESENIUS KABI ONCOLOGY LIMITED; MISHRA, Bhuwan Bhaskar; KACHHADIA, Nikunj Shambhubhai; TOMAR, Vinod Singh; LAHIRI, Saswata
Patent: US2014/121383 A1, 2014 ;
Location in patent: Paragraph 0094 ;

3543-73-55-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯+

540-51-22-溴乙醇

3543-74-6[1-甲基-2-(4’-丁酸乙酯基)-5-N, N-二(2’-羟基乙基)]-1H -苯并咪唑

参考文献

FRESENIUS KABI ONCOLOGY LIMITED; MISHRA, Bhuwan Bhaskar; KACHHADIA, Nikunj Shambhubhai; TOMAR, Vinod Singh; LAHIRI, Saswata
Patent: US2014/121383 A1, 2014 ;
Location in patent: Paragraph 0086; 0087 ;

157-18-6+

3543-73-55-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯

3543-74-6[1-甲基-2-(4’-丁酸乙酯基)-5-N, N-二(2’-羟基乙基)]-1H -苯并咪唑

参考文献

FRESENIUS KABI ONCOLOGY LTD.; MISHRA, Bhuwan Bhaskar; KACHHADIA, Nikunj Shambhubhai; TOMAR, Vinod Singh; LAHIRI, Saswata
Patent: WO2013/46223 A1, 2013 ;
Location in patent: Page/Page column 24 ;

3543-73-55-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯+

540-51-22-溴乙醇

参考文献

HEYL Chemisch-Pharmazeutische Fabrik GmbH und Co. KG; Frey, Michael; Walther, Dirk-Detlef
Patent: EP2690096 A1, 2014 ;
Location in patent: Paragraph 0079; 0080 ;

3543-73-55-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯+

107-07-32-氯乙醇

3543-74-6[1-甲基-2-(4’-丁酸乙酯基)-5-N, N-二(2’-羟基乙基)]-1H -苯并咪唑

参考文献

BIOPHORE INDIA PHARMACEUTICALS PVT. LTD.; PULLAGURLA, Manik Reddy; RANGISETTY, Jagadeesh Babu; PRESLEY, S., I., Davis; NAGARAPU, Radha
Patent: WO2012/7966 A2, 2012 ;
Location in patent: Page/Page column 4-5 ;

3543-73-55-氨基-1-甲基-1H-苯并咪唑-2-丁酸乙酯

3543-75-7

参考文献

US2013/317234 A1, ;