3,4-二甲氧基苯甲酰氯合成路线 （共 99 条）
反应条件
1: diethyl ether / 0 °C 2: aq. Ag2O / dioxane View Scheme
参考文献
Young, Jonathan R.; Huang, Song X.; Chen, Irene; Walsh, Thomas F.; DeVita, Robert J.; Wyvratt Jr., Matthew J.; Goulet, Mark T.; Ren, Ning; Lo, Jane; Yang, Yi Tien; Yudkovitz, Joel B.; Cheng, Kang; Smith, Roy G.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1723 - 1727
反应条件
1: 1.) Lithium diisopropylamide / THF 2: 87 percent / conc. H2SO4 / acetic acid View Scheme
参考文献
Banerji, Asoke; Goomer, Naresh C.
Synthesis, 1980 , # 11 p. 874 - 875
反应条件
potassium carbonate; toluene-4-sulfonic acid; tetra(n-butyl)ammonium hydrogensulfate 1.) benzene, 80 deg C, 3 h, 2.) benzene, reflux, 45 min; Yield given. Multistep reaction;
参考文献
Jain, P. K.; Makrandi, J. K.; Grover, S. K.
Synthesis, 1982 , # 3 p. 221 - 222
反应条件
1.1: tetrahydrofuran / 12 h / 20 °C 2.1: potassium ethylxanthate; copper diacetate / N,N-dimethyl-formamide / 15 h / 80 °C / |Inert atmosphere 2.2: 8 h / 20 °C View Scheme
参考文献
Prasad; Sekar
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 10 p. 1659 - 1665
参考文献
Vejdelek et al.
Collection of Czechoslovak Chemical Communications, 1957 , vol. 22, p. 98,102
参考文献
Chang, Mingxin; Li, Wei; Zhang, Xumu
Angewandte Chemie - International Edition, 2011 , vol. 50, # 45 p. 10679 - 10681
反应条件
carbon disulfide; aluminium trichloride und Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts mit AlCl3 in Toluol;
参考文献
Russell; Butler
Journal of the American Chemical Society, 1949 , vol. 71, p. 3663
反应条件
triethylamine in toluene T=75 - 80°C; 2 h; Heating / reflux;
参考文献
ERREGIERRE S.p.A.
Patent: WO2006/51079 A1, 2006 ;
Location in patent: Page/Page column 6-7 ;
反应条件
triethylamine in chloroform 2 h; Ambient temperature; Yield given;
参考文献
Sakaguchi; Nishino; Ogawa; Iwanaga; Yasuda; Kato; Ito
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 1 p. 202 - 211
反应条件
1: 1.) n-BuLi, N-isopropylcyclohexylamine / 1.) THF, hexane, -78 deg C, 15 min, 2.) THF, hexane, -78 deg C, 15 min 2: 4.5 h / Mortierella isabelina View Scheme
参考文献
Jung, Jae-Chul; Park, Oee-Sook
Synthetic Communications, 2007 , vol. 37, # 10 p. 1665 - 1673
