(E)-3-羟基-5-甲氧基二苯乙烯合成路线 （共 13 条）
反应条件
boron tribromide in dichloromethane T=-78°C; 12 h;
参考文献
Kabir, M. Shahjahan; Engelbrecht, Kathleen; Polanowski, Rebecca; Krueger, Sarah M.; Ignasiak, Rachel; Rott, Marc; Schwan, William R.; Stemper, Mary E.; Reed, Kurt D.; Sherman, David; Cook, James M.; Monte, Aaron
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 21 p. 5745 - 5749
反应条件
boron tribromide in dichloromethane T=0 - 20°C;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 5 p. 1130 - 1136
反应条件
1.1: NaOMe / dimethylformamide / 0 °C 1.2: dimethylformamide / 20 °C 2.1: 40 percent / BBr3 / -80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5895 - 5898
反应条件
1.1: NaOMe / dimethylformamide / 0 °C 1.2: dimethylformamide / 20 °C 2.1: 40 percent / BBr3 / -80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5895 - 5898
反应条件
1.1: 130 °C 2.1: NaOMe / dimethylformamide / 0 °C 2.2: dimethylformamide / 20 °C 3.1: 40 percent / BBr3 / -80 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5895 - 5898
反应条件
1: 1.) potassium tert-butoxide, 2.) diphenyl disulfide / 1.) THF, 30 min, 2.) THF, reflux, 4 h 2: 43 percent / BBr3 / CH2Cl2 / 0 - 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 40, # 5 p. 1130 - 1136
反应条件
1: 96.4 percent / H2 / 10percent Pd-C / ethyl acetate / 2 h / Ambient temperature 2: 919.1 mg / KI, K2CO3 / acetone / 43 h / 80 °C 3: 84.5 percent / H2, quinoline / Pd-BaSO4 / ethyl acetate 4: 13.5 percent / silica gel / hexane; benzene / 12 h / Ambient temperature; or in xylene at 130 deg C, 16 h View Scheme
参考文献
Asakawa, Yoshinori; Kondo, Keiko; Tori, Motoo; Hashimoto, Toshihiro; Ogawa, Shunichi
Phytochemistry (Elsevier), 1991 , vol. 30, # 1 p. 219 - 234
反应条件
1: 96.4 percent / H2 / 10percent Pd-C / ethyl acetate / 2 h / Ambient temperature 2: 919.1 mg / KI, K2CO3 / acetone / 43 h / 80 °C 3: 84.5 percent / H2, quinoline / Pd-BaSO4 / ethyl acetate 4: 13.5 percent / silica gel / hexane; benzene / 12 h / Ambient temperature; or in xylene at 130 deg C, 16 h 5: 17.7 percent / EtSNa / hexamethylphosphoric acid triamide / 5 h / 170 - 180 °C View Scheme
参考文献
Asakawa, Yoshinori; Kondo, Keiko; Tori, Motoo; Hashimoto, Toshihiro; Ogawa, Shunichi
Phytochemistry (Elsevier), 1991 , vol. 30, # 1 p. 219 - 234
反应条件
hydrogen; palladium on activated charcoal in ethanol 1 h;
参考文献
Ali; Kondo; Tsuda
Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 5 p. 1130 - 1136
反应条件
pyridine hydrochloride T=180°C;
参考文献
Lindstedt
Acta Chemica Scandinavica (1947-1973), 1949 , vol. 3, p. 912
