1-(4-噻吩-2-苯基)-乙酮合成路线 （共 23 条）
反应条件
water; potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether Substitution;
参考文献
Kotha, Sambasivarao; Kashinath, Dhurke; Lahiri, Kakali; Sunoj, Raghavan B.
European Journal of Organic Chemistry, 2004 , # 19 p. 4003 - 4013
反应条件
palladium diacetate in N,N-dimethyl-formamide T=50°C;
参考文献
Yamamoto, Yasunori; Takizawa, Miho; Yu, Xiao-Qiang; Miyaura, Norio
Angewandte Chemie - International Edition, 2008 , vol. 47, # 5 p. 928 - 931
反应条件
potassium carbonate; Tedicyp; bis(η3-allyl-μ-chloropalladium(II)) in xylene T=130°C; Suzuki coupling reaction; 20 h;
参考文献
Kondolff, Isabelle; Doucet, Henri; Santelli, Maurice
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 1 p. 109 - 118
反应条件
silver carbonate; [(P(OCH(CF3)2)3)2Rh(CO)Cl] in ethylene glycol dimethyl ether; m-xylene T=150°C; 14 h; microwave irradiation;
参考文献
Yanagisawa, Shuichi; Sudo, Tomoko; Noyori, Ryoji; Itami, Kenichiro
Tetrahedron, 2008 , vol. 64, # 26 p. 6073 - 6081
反应条件
1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox; 2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol T=80°C; Suzuki-Miyaura Coupling; 4 h; Inert atmosphereGlovebox;
参考文献
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259,12
Title/Abstract Full Text Show Details
Yang, Junfeng; Liu, Sijia; Zheng, Jian-Feng; Zhou, Jianrong
European Journal of Organic Chemistry, 2012 , # 31 p. 6248 - 6259
反应条件
potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=130°C; 20 h; Inert atmosphere;
参考文献
Bensaid, Souhila; Roger, Julien; Beydoun, Kassem; Roy, David; Doucet, Henri
Synthetic Communications, 2011 , vol. 41, # 23 p. 3524 - 3531
反应条件
Pd/BMI-TFSI; caesium carbonate in water T=80°C; Suzuki-Miyaura coupling; Inert atmosphere;
参考文献
Oda, Yoshiro; Hirano, Koji; Yoshii, Kazuki; Kuwabata, Susumu; Torimoto, Tsukasa; Miura, Masahiro
Chemistry Letters, 2010 , vol. 39, # 10 p. 1069 - 1071
反应条件
1: 2-Iodothiophene With chloro-trimethyl-silane; ethylene dibromide; lithium chloride; zinc in tetrahydrofuran T=25°C; 0.5 h; Inert atmosphere; 2: para-bromoacetophenone With PEPPSI-IPr catalyst in tetrahydrofuran T=25°C; Negishi cross-coupling; 1 h; Inert atmosphere;
参考文献
Sase, Shohei; Jaric, Milica; Metzger, Albrecht; Malakhov, Vladimir; Knochel, Paul
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7380 - 7382
反应条件
potassium fluoride; bis(η3-allyl-μ-chloropalladium(II)) in N,N-dimethyl-formamide T=100°C; 24 h;
参考文献
Hatanaka, Yasuo; Fukushima, Satoshi; Hiyama, Tamejiro
Heterocycles, 1990 , vol. 30, # 1 p. 303 - 306
反应条件
palladium 10 on activated carbon; LiF in 1-methyl-pyrrolidin-2-one T=120°C; Stille coupling; 24 h;
参考文献
Yabe, Yuki; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao
Tetrahedron, 2010 , vol. 66, # 45 p. 8654 - 8660
